sodium hydroxide in water; butan-1-ol Ambient temperature;
参考文献
Litvinenko, L. M.; Kosmynin, V. V.; Kaida, L. N.; Savelova, V. A.; Verbovaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 4 p. 784 - 785
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 4 p. 877 - 878
1: 96 percent / N,N'-dicyclohexylcarbodiimide / Ambient temperature; in THF or in CH2Cl2 2: 67 percent / Ambient temperature 3: 34 percent / N,N'-dicyclohexylcarbodiimide / Ambient temperature; in THF or in CH2Cl2 4: 70 percent / Ambient temperature View Scheme
hydrogenchloride; N-lt;lt;lt;(benzyloxycarbonyl)aminogt;methylgt;hydroxyphosphinylgt;-L-phenylalanine; tri-(hydroxymethyl)-methylamine; sodium chloride; carboxypeptidase A in water T=25°C; competitive inhibition (rapid and reversible) of CPA-catalyzed peptide hydrolysis, Ki at this pH and pH = 6.0; effect of added ZnCl2 on inhibition; Mechanism;
参考文献
Jacobsen,N.E.; Bartlett,P.A.
Journal of the American Chemical Society, 1981 , vol. 103, p. 654