1,4-双(4,5-二氢-2-恶唑)苯合成路线 (共 12 条)
反应条件
trichloroisocyanuric acid in neat (no solvent) T=110°C; 6.5 h; chemoselective reaction;
参考文献
Hojati, Seyedeh Fatemeh; Nezhadhoseiny, Seyede Atefe
Journal of the Serbian Chemical Society, 2012 , vol. 77, # 9 p. 1181 - 1189,9
反应条件
triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=20°C; 24 h; Inert atmosphere;
参考文献
Xu, Quancai; Li, Zhengning; Chen, Huiying
Chinese Journal of Chemistry, 2011 , vol. 29, # 5 p. 925 - 932
反应条件
potassium fluoride on basic alumina in acetonitrile 24 h;
参考文献
Mitchell; Benicewicz
Synthesis, 1994 , # 7 p. 675 - 677
反应条件
pyridinium hydrobromide perbromide T=20°C; 40 h;
参考文献
Synlett, , # 10 p. 1479 - 1484
反应条件
tetrachloromethane; triethylamine; triphenylphosphine in pyridine; acetonitrile Ambient temperature;
参考文献
Vorbruggen; Krolikiewicz
Tetrahedron, 1993 , vol. 49, # 41 p. 9353 - 9372
反应条件
sodium hydroxide in water 1) 20 deg C 15 h 2)reflux 5 h;
参考文献
Belen'kii, L. I.; Cheskis, M. A.; Zvolinskii, V. P.; Obukhov, A. E.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 6 p. 654 - 663
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 6 p. 826 - 836
反应条件
sodium acetate T=100°C;
参考文献
Chemistry - An Asian Journal, , vol. 8, # 7 p. 1408 - 1411
参考文献
Russian Chemical Bulletin, , vol. 45, # 10 p. 2378 - 2379
反应条件
1: NaOEt / ethanol / Heating 2: SOCl2 3: NaOH / methanol / 1 h / Heating View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , p. 1455 - 1464
反应条件
1: sodium acetate / 100 °C 2: sodium acetate / 100 °C View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 8, # 7 p. 1408 - 1411