1: With hydroxylamine hydrochloride in water 1 h; 2: With sodium dihydrogen phosphate monohydrate; bromine; sodium hydroxide in water T=10 - 15°C; Cooling with ice;
参考文献
F. HOFFMANN-LA ROCHE AG; BUETTELMANN, Bernd; JAKOB-ROETNE, Roland; KNUST, Henner; LUCAS, Matthew C.; THOMAS, Andrew
Patent: WO2010/127978 A1, 2010 ;
Location in patent: Page/Page column 51 ;
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in water Br2 is led into the suspension under cooling; dibromofuroxane distilled with water vapor distillation; dibromofuroxim extracted with ether and distilled in vacuum;
