hydrogen; palladium 10 on activated carbon in ethanol T=20°C; P=750.075 Torr; 1 h;

potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane RefluxInert atmosphere;

potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane Inert atmosphereReflux;

1: tetra-(n-butyl)ammonium iodide; sodium carbonate / dichloromethane; water / 144 h / Reflux 2: potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / 1,4-dioxane / 15 h / Inert atmosphere; Reflux 3: hydrogen / palladium 10 on activated carbon / ethanol / 1 h / 20 °C / 750.08 Torr View Scheme

1: potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / 1,4-dioxane / 15 h / Inert atmosphere; Reflux 2: hydrogen / palladium 10 on activated carbon / ethanol / 1 h / 20 °C / 750.08 Torr View Scheme