2-[3-(4-溴苯甲酰基)苯氧基]丙酸合成路线 (共 4 条)
反应条件
water; sodium carbonate in ethanol
Ambient temperature;
参考文献
Astoin; Lepage; Fromantin
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 457 - 462
反应条件
1: 65 percent / aluminium trichloride / 1.) room temp., 1.5 h, 2.) reflux, 2 h
2: 83 percent / potassium carbonate / dimethylformamide / 4 h / 80 °C
3: 79 percent / 1.) H2O, sodium carbonate, 2.) acid / ethanol / Ambient temperature
View Scheme
参考文献
Astoin; Lepage; Fromantin
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 457 - 462
反应条件
1: 83 percent / potassium carbonate / dimethylformamide / 4 h / 80 °C
2: 79 percent / 1.) H2O, sodium carbonate, 2.) acid / ethanol / Ambient temperature
View Scheme
参考文献
Astoin; Lepage; Fromantin
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 457 - 462
反应条件
1: 65 percent / aluminium trichloride / 1.) room temp., 1.5 h, 2.) reflux, 2 h
2: 83 percent / potassium carbonate / dimethylformamide / 4 h / 80 °C
3: 79 percent / 1.) H2O, sodium carbonate, 2.) acid / ethanol / Ambient temperature
View Scheme
参考文献
Astoin; Lepage; Fromantin
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 5 p. 457 - 462