(1R,8R)-7-亚甲基-1,2,3,5,6,8-六氢吡咯里嗪-1-醇合成路线 （共 8 条）
反应条件
tetrachloromethane; triethylamine; triphenylphosphine in N,N-dimethyl-formamide
T=20°C; Yield given;
参考文献
Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606
反应条件
1: Zn, NH4Cl / 2-methyl-propan-2-ol; H2O / 0 - 20 °C
2: 6N HCl / methanol / 20 °C
3: CCl4, Ph3P, Et3N / dimethylformamide / 20 °C
View Scheme
参考文献
Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606
反应条件
1: DBU / acetonitrile / 0 °C
2: I2, K2CO3 / acetonitrile / 0 - 20 °C
3: Zn, NH4Cl / 2-methyl-propan-2-ol; H2O / 0 - 20 °C
4: 6N HCl / methanol / 20 °C
5: CCl4, Ph3P, Et3N / dimethylformamide / 20 °C
View Scheme
参考文献
Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606
反应条件
1: DBU / acetonitrile / 0 °C
2: I2, K2CO3 / acetonitrile / 0 - 20 °C
3: Zn, NH4Cl / 2-methyl-propan-2-ol; H2O / 0 - 20 °C
4: 6N HCl / methanol / 20 °C
5: CCl4, Ph3P, Et3N / dimethylformamide / 20 °C
View Scheme
参考文献
Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606
反应条件
1: I2, K2CO3 / acetonitrile / 0 - 20 °C
2: Zn, NH4Cl / 2-methyl-propan-2-ol; H2O / 0 - 20 °C
3: 6N HCl / methanol / 20 °C
4: CCl4, Ph3P, Et3N / dimethylformamide / 20 °C
View Scheme
参考文献
Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606
反应条件
1: 37.7 percent / aq. Ba(OH)2*8H2O / 16 h / Heating
2: SOCl2 / 0 °C
3: Zn, 1 M aq. H2SO4
View Scheme
参考文献
Logie, Catherine G.; Liddell, J. Richard; Kaye, Perry T.
South African Journal of Chemistry, 1997 , vol. 50, # 2 p. 72 - 74
反应条件
1: SOCl2 / 0 °C
2: Zn, 1 M aq. H2SO4
View Scheme
参考文献
Logie, Catherine G.; Liddell, J. Richard; Kaye, Perry T.
South African Journal of Chemistry, 1997 , vol. 50, # 2 p. 72 - 74
反应条件
sulfuric acid; zinc
Title compound not separated from byproducts;
参考文献
Logie, Catherine G.; Liddell, J. Richard; Kaye, Perry T.
South African Journal of Chemistry, 1997 , vol. 50, # 2 p. 72 - 74
