hydrogen; palladium on activated charcoal in methanol; ethyl acetate Ambient temperature;

1: 83 percent / K2CO3, KI / acetone; dimethylformamide / Heating 2: 75 percent / AlBr3, NaI / acetonitrile / 0.25 h / 0 °C 3: pyridine / 2 h / 70 - 80 °C 4: KOH / pyridine / 80 °C 5: 92 percent / conc. H2SO4, acetic acid / 1 h / 50 °C 6: 74 percent / dimethyldioxirane / acetone / 0 °C 7: 85 percent / K2CO3 / acetone / Heating 8: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 9: 88 percent / K2CO3 / methanol / 1.5 h / Heating 10: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: K2CO3 / dimethylformamide / 0.17 h / 150 °C 2: 100 percent / conc. HCl, acetic acid / 1 h / Ambient temperature 3: 83 percent / K2CO3, KI / acetone; dimethylformamide / Heating 4: 75 percent / AlBr3, NaI / acetonitrile / 0.25 h / 0 °C 5: pyridine / 2 h / 70 - 80 °C 6: KOH / pyridine / 80 °C 7: 92 percent / conc. H2SO4, acetic acid / 1 h / 50 °C 8: 74 percent / dimethyldioxirane / acetone / 0 °C 9: 85 percent / K2CO3 / acetone / Heating 10: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 11: 88 percent / K2CO3 / methanol / 1.5 h / Heating 12: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: pyridine / 2 h / 70 - 80 °C 2: KOH / pyridine / 80 °C 3: 92 percent / conc. H2SO4, acetic acid / 1 h / 50 °C 4: 74 percent / dimethyldioxirane / acetone / 0 °C 5: 85 percent / K2CO3 / acetone / Heating 6: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 7: 88 percent / K2CO3 / methanol / 1.5 h / Heating 8: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 75 percent / AlBr3, NaI / acetonitrile / 0.25 h / 0 °C 2: pyridine / 2 h / 70 - 80 °C 3: KOH / pyridine / 80 °C 4: 92 percent / conc. H2SO4, acetic acid / 1 h / 50 °C 5: 74 percent / dimethyldioxirane / acetone / 0 °C 6: 85 percent / K2CO3 / acetone / Heating 7: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 8: 88 percent / K2CO3 / methanol / 1.5 h / Heating 9: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 74 percent / dimethyldioxirane / acetone / 0 °C 2: 85 percent / K2CO3 / acetone / Heating 3: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 4: 88 percent / K2CO3 / methanol / 1.5 h / Heating 5: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 92 percent / conc. H2SO4, acetic acid / 1 h / 50 °C 2: 74 percent / dimethyldioxirane / acetone / 0 °C 3: 85 percent / K2CO3 / acetone / Heating 4: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 5: 88 percent / K2CO3 / methanol / 1.5 h / Heating 6: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 85 percent / K2CO3 / acetone / Heating 2: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 3: 88 percent / K2CO3 / methanol / 1.5 h / Heating 4: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 88 percent / K2CO3 / methanol / 1.5 h / Heating 2: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 83 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 2: 88 percent / K2CO3 / methanol / 1.5 h / Heating 3: 89 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme