N-苯基氮杂环庚烷-4-胺合成路线 （共 6 条）
反应条件
hydrogen bromide
3 h; Heating;
参考文献
De Ruiter; Andurkar; Riley; Walters; Noggle Jr.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 779 - 786
Title/Abstract View citing articles Show Details
Finney, Z. Gail; Riley, Thomas N.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 895 - 899
反应条件
1: 4 N HCl / 6 h / Heating
2: 30percent aq. K2CO3 / 4 h / -5 °C
3: ZnCl2 / toluene / 15 h / Heating
4: NaBH4 / methanol / 1 h / Heating
5: 85 percent / 48percent HBr / 3 h / Heating
View Scheme
参考文献
Finney, Z. Gail; Riley, Thomas N.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 895 - 899
反应条件
1: 52.5 g / BF3*Et2O / diethyl ether / 1 h / -30 - -25 °C
2: 4 N HCl / 6 h / Heating
3: 30percent aq. K2CO3 / 4 h / -5 °C
4: ZnCl2 / toluene / 15 h / Heating
5: NaBH4 / methanol / 1 h / Heating
6: 85 percent / 48percent HBr / 3 h / Heating
View Scheme
参考文献
Finney, Z. Gail; Riley, Thomas N.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 895 - 899
反应条件
1: ZnCl2 / toluene / 15 h / Heating
2: NaBH4 / methanol / 1 h / Heating
3: 85 percent / 48percent HBr / 3 h / Heating
View Scheme
参考文献
De Ruiter; Andurkar; Riley; Walters; Noggle Jr.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 779 - 786
Title/Abstract View citing articles Show Details
Finney, Z. Gail; Riley, Thomas N.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 895 - 899
反应条件
1: 30percent aq. K2CO3 / 4 h / -5 °C
2: ZnCl2 / toluene / 15 h / Heating
3: NaBH4 / methanol / 1 h / Heating
4: 85 percent / 48percent HBr / 3 h / Heating
View Scheme
参考文献
Finney, Z. Gail; Riley, Thomas N.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 895 - 899
反应条件
1: K2CO3 / H2O / 4 h / -5 °C
2: ZnCl2 / toluene / 15 h / Heating
3: NaBH4 / methanol / 1 h / Heating
4: 85 percent / 48percent HBr / 3 h / Heating
View Scheme
参考文献
De Ruiter; Andurkar; Riley; Walters; Noggle Jr.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 779 - 786
