N-(1,1'-联苯)-2-基苯甲酰胺合成路线 （共 21 条）
反应条件
[bis(acetoxy)iodo]benzene in hexafluoroisopropyl alcohol T=20°C; 3 h;
参考文献
Antonchick, Andrey P.; Samanta, Rajarshi; Kulikov, Katharina; Lategahn, Jonas
Angewandte Chemie - International Edition, 2011 , vol. 50, # 37 p. 8605 - 8608
反应条件
triethylamine in dichloromethane
T=20°C; 1 h;
参考文献
Tsang, W. C. Peter; Munday, Rachel H.; Brasche, Gordon; Zheng, Nan; Buchwald, Stephen L.
Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7603 - 7610
反应条件
silver fluoride; copper(II) bis(trifluoromethanesulfonate); palladium diacetate in 1,4-dioxane
T=110°C; 48 h;
参考文献
Yang, Shangdong; Li, Bijie; Wan, Xiaobing; Shi, Zhangjie
Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6066 - 6067
反应条件
aluminium trichloride in benzene
3 h; Ambient temperature;
参考文献
Tashiro, Masashi; Fukuda, Yasuhisa; Yamato, Takehiko
Journal of Organic Chemistry, 1983 , vol. 48, # 11 p. 1927 - 1928
反应条件
1.1: potassium carbonate / bis(triphenylphosphine)palladium(II)-chloride / N,N-dimethyl-formamide; water / 24 h / 80 °C
2.1: chloroform / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice
2.2: 3 h / 20 °C / Reflux
View Scheme
参考文献
ROCHE DIAGNOSTICS GMBH; F. HOFFMANN-LA ROCHE AG; WESTFAeLISCHE WILHELMS-UNIVERSITAeT MUeNSTER; CYSEWSKI, Robert; DE COLA, Luisa; FERNANDEZ HERNANDEZ, Jesus Miguel; JOSEL, Hans-Peter; LOPEZ-CALLE, Eloisa; ZARNT, Toralf
Patent: WO2012/107419 A1, 2012 ;
反应条件
1.1: potassium carbonate / bis(triphenylphosphine)palladium(II)-chloride / N,N-dimethyl-formamide; water / 24 h / 80 °C
2.1: chloroform / 0.5 h / 20 °C / Inert atmosphere; Cooling with ice
2.2: 3 h / 20 °C / Reflux
View Scheme
参考文献
ROCHE DIAGNOSTICS GMBH; F. HOFFMANN-LA ROCHE AG; WESTFAeLISCHE WILHELMS-UNIVERSITAeT MUeNSTER; CYSEWSKI, Robert; DE COLA, Luisa; FERNANDEZ HERNANDEZ, Jesus Miguel; JOSEL, Hans-Peter; LOPEZ-CALLE, Eloisa; ZARNT, Toralf
Patent: WO2012/107419 A1, 2012 ;
反应条件
1: 96 percent
2: 63 percent / aluminum chloride / benzene / 3 h / Ambient temperature
View Scheme
参考文献
Tashiro, Masashi; Fukuda, Yasuhisa; Yamato, Takehiko
Journal of Organic Chemistry, 1983 , vol. 48, # 11 p. 1927 - 1928
反应条件
1: 96 percent
2: 63 percent / aluminum chloride / benzene / 3 h / Ambient temperature
View Scheme
参考文献
Tashiro, Masashi; Fukuda, Yasuhisa; Yamato, Takehiko
Journal of Organic Chemistry, 1983 , vol. 48, # 11 p. 1927 - 1928
反应条件
1: n-BuONO / HCl / acetic acid / 2 h / -10 °C
2: 70 percent / pyridine / 0.17 h / 70 °C
3: 55 percent / HCl / acetic acid; acetic anhydride / 2 h / 100 °C / hydroxyiminocyclohexenes
View Scheme
参考文献
Sivasubramanian, S.; Muthusubramanian, S.; Ramasamy, S.; Arumugam, N
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 7 p. 552 - 554
反应条件
1: 55 percent / HCl / acetic acid; acetic anhydride / 2 h / 100 °C / hydroxyiminocyclohexenes
View Scheme
参考文献
Sivasubramanian, S.; Muthusubramanian, S.; Ramasamy, S.; Arumugam, N
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 7 p. 552 - 554
