4-甲基-4-苯基-2-戊酮合成路线 （共 43 条）
反应条件
1: aq. NaOH, Br2 2: LiAlH4 / diethyl ether View Scheme
参考文献
Abramovici,M.; Pines,H.
Journal of Organic Chemistry, 1969 , vol. 34, p. 266 - 270
参考文献
Barnes; Beitchman
Journal of the American Chemical Society, 1954 , vol. 76, p. 5430,5432
反应条件
1: 71 percent / ammonia; KOH / ethanol / 20 °C 2: 76 percent / tetraethylammonium bromide; CuBr; triethylamine / 100 °C / 167200 Torr 3: 91 percent / polyphosphoric acid / 0.5 h / 80 °C 4: 20 percent / LiAlH4 / dioxane / 8 h / Heating View Scheme
参考文献
Chudinov; Gashev; Chernysheva; Semenov
Russian Chemical Bulletin, 2006 , vol. 55, # 1 p. 123 - 136
反应条件
1: aqueous sodium hypochlorite solution 2: benzene; phosphorus (V)-chloride 3: AlCl3; benzene 4: 20 °C 5: glacial acetic acid; H2SO4 6: chromium (VI)-oxide; acetic acid View Scheme
参考文献
Koelsch; LeClaire
Journal of Organic Chemistry, 1941 , vol. 6, p. 516,531
参考文献
Hoffman
Journal of the American Chemical Society, 1929 , vol. 51, p. 2545
反应条件
(i) Et2O, (ii) (heating), H2SO4, (iii) H2, Pd-C, EtOAc; Multistep reaction;
参考文献
Zwierzak,A.; Pines,H.
Journal of Organic Chemistry, 1963 , vol. 28, p. 3392 - 3399
反应条件
1: Br2, alkaline 2: 1.) PCl5, 2.) AlCl3 / 1) C6H6 3: KNO3, H2SO4 / 0 °C 4: 1.) H2, 2.) NaNO2, HCl, 3.) H2SO4, H2O / 1.) PtO / 2) 0 deg C; 3) heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 17 p. 5618 - 5626
反应条件
1: Br2, alkaline 2: 1.) PCl5, 2.) AlCl3 / 1) C6H6 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 17 p. 5618 - 5626
反应条件
1: aq. NaOH, Br2 2: LiAlH4 / diethyl ether 3: PBr3 View Scheme
参考文献
Pines,H.; Sih,N.C.
Journal of Organic Chemistry, 1965 , vol. 30, p. 280 - 284
反应条件
AlCl3, aluminium chloride
T=0 - 20°C; 4 h;
参考文献
Tsang, Kwok Yin; Sinha, Santosh; Liu, Xiaoxia; Bhat, Smita; Chandraratna, Roshantha A.
Patent: US2005/148590 A1, 2005 ;
Location in patent: Page/Page column 25; 26 ;
