5-羟基-6,7-二甲氧基黄酮合成路线 （共 18 条）
反应条件
water; hydrogen bromide; acetic acid 3 h; Reflux;
参考文献
Righi, Giuliana; Antonioletti, Roberto; Silvestri, Ilaria Proietti; D'Antona, Nicola; Lambusta, Daniela; Bovicelli, Paolo
Tetrahedron, 2010 , vol. 66, # 6 p. 1294 - 1298
反应条件
1: pyridine; aqueous KOH-solution; aqueous potassium peroxo disulfate solution / anschliessendes Erwaermen mit Natriumsulfit und wss. Salzsaeure 2: acetone; potassium carbonate View Scheme
参考文献
Murti et al.
Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186
反应条件
in tetrahydrofuran; methanol; hexane
T=20°C; 8 h;
参考文献
YALE UNIVERSITY
Patent: WO2005/75449 A1, 2005 ;
Location in patent: Page/Page column 30 ;
WO 2005/075449 A1
反应条件
boron trichloride in dichloromethane
T=0°C; 0.5 h; regioselective reaction;
参考文献
Wang, Jun-Fei; Ding, Ning; Zhang, Wei; Wang, Peng; Li, Ying-Xia
Helvetica Chimica Acta, 2011 , vol. 94, # 12 p. 2221 - 2230
反应条件
1: sodium methylate With copper(I) bromide in methanol; N,N-dimethyl-formamide
T=20°C; 1 h;
2: C18H13BrO5 in methanol; N,N-dimethyl-formamide
T=120°C; 0.666667 h;
3: With hydrogenchloride in methanol; water; N,N-dimethyl-formamide
T=20°C; Cooling;
参考文献
Righi, Giuliana; Antonioletti, Roberto; Silvestri, Ilaria Proietti; D'Antona, Nicola; Lambusta, Daniela; Bovicelli, Paolo
Tetrahedron, 2010 , vol. 66, # 6 p. 1294 - 1298
反应条件
1: sodium methylate With copper(I) bromide in methanol; N,N-dimethyl-formamide
T=20°C; 1 h;
2: 8-Brom-5-acetoxy-7-methoxy-flavon in methanol; N,N-dimethyl-formamide
T=120°C; 5 h;
3: With hydrogenchloride in methanol; water; N,N-dimethyl-formamide
T=20°C; Cooling;
参考文献
Righi, Giuliana; Antonioletti, Roberto; Silvestri, Ilaria Proietti; D'Antona, Nicola; Lambusta, Daniela; Bovicelli, Paolo
Tetrahedron, 2010 , vol. 66, # 6 p. 1294 - 1298
反应条件
potassium carbonate in acetone
2 h; Heating;
参考文献
Gao, Hong; Nishioka, Tetsuo; Kawabata, Jun; Kasai, Takanori
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 2 p. 369 - 375
反应条件
1: Tectochrysin With tetra-n-butylammonium tribromide in chloroform
T=20°C; 2 h;
2: sodium methylate With copper(I) bromide in methanol; N,N-dimethyl-formamide
T=120°C; 5 h;
3: With hydrogenchloride in methanol; water; N,N-dimethyl-formamide
T=20°C; Cooling;
参考文献
Righi, Giuliana; Antonioletti, Roberto; Silvestri, Ilaria Proietti; D'Antona, Nicola; Lambusta, Daniela; Bovicelli, Paolo
Tetrahedron, 2010 , vol. 66, # 6 p. 1294 - 1298
反应条件
potassium carbonate in acetone
3 h; Heating;
参考文献
Suresh Babu; Hari Babu; Srinivas; Sastry; Hara Kishore; Murty; Madhusudana Rao
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3953 - 3956
反应条件
1: 0.35 g / aq. KOH / ethanol / 24 h / 30 °C
2: 0.15 g / selenium dioxide / pentan-1-ol / 24 h / Heating
3: 0.27 g / AlCl3 / acetonitrile / 24 h / Heating
View Scheme
参考文献
Parmar, Virinder S.; Gupta, Sandhya; Sinha, Rita; Sharma, Sunil K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 2 p. 244 - 256
