二乙基(2-苯氧基乙基)胺合成路线 （共 9 条）
反应条件
sodium hydroxide in water
T=20 - 55°C; 5.16 h;
参考文献
SANOFI; Grimaud, Bernard; Grossi, Pierre-Jean
Patent: US2014/18553 A1, 2014 ;
Location in patent: Paragraph 0273-0276 ;
反应条件
potassium carbonate in acetone
T=60°C; 6 h;
参考文献
Sharma; Rani; Talwar; Kalsi
Journal of the Indian Chemical Society, 1991 , vol. 68, # 3 p. 135 - 137
反应条件
ethanol; sodium iodide
参考文献
Burger et al.
Journal of the American Chemical Society, 1945 , vol. 67, p. 1416,1417
反应条件
in toluene
T=111°C; 2 h;
参考文献
Katritzky; Burgess; Patel
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 4 p. 741 - 745
反应条件
1: 72 percent / 2) Acetic acid / CH2Cl2 / 1) 40 min, 2) 2 h.
2: 57 percent / toluene / 2 h / 111 °C
View Scheme
参考文献
Katritzky; Burgess; Patel
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 4 p. 741 - 745
反应条件
potassium hydroxide; ethanol
T=140°C;
参考文献
Slotta; Behnisch
Justus Liebigs Annalen der Chemie, 1932 , vol. 497, p. 171,175, 178
反应条件
ethanol
T=110 - 130°C;
参考文献
Kuroda; Koyama
Yakugaku Zasshi, 1943 , vol. 63, p. 387,389
Chem.Abstr., 1951 , p. 3350
参考文献
Crosby,J.; Stirling,C.J.M.
Journal of the Chemical Society [Section] B: Physical Organic, 1970 , p. 671 - 679
参考文献
Crosby,J.; Stirling,C.J.M.
Journal of the Chemical Society [Section] B: Physical Organic, 1970 , p. 671 - 679
