(2R,3R,4S)-3-乙酰氨基-4-乙酰氧基-2-((1R,2R)-1,2,3-三乙酰氧基丙基)-3,4-二氢-2H-吡喃-6-羧酸甲酯合成路线 （共 94 条）
反应条件
in benzene 17 h; Ambient temperature;
参考文献
Carbohydrate Research, , vol. 104, p. 221 - 234
反应条件
N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve 1.) CH3CN, RT, 30 min, 2.) CH3CN, -60 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 23, # 9 p. 683 - 691
反应条件
N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve 1.) acetonitrile, RT, 30 min, 2.) acetonitrile, -60 deg C to RT, 1 h; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 25, # 1 p. 55 - 61
反应条件
N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve 1.) acetonitrile, RT, 30 min, 2.) acetonitrile, -60 deg C - RT, 30 min; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 25, # 1 p. 55 - 61
反应条件
Multistep reaction. Further byproducts.;
参考文献
Carbohydrate Research, , vol. 343, # 5 p. 936 - 940
反应条件
N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; toluene-4-sulfonic acid Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 23, # 9 p. 683 - 691
反应条件
1: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 2: 50percent aq. AcOH / ethyl acetate / Ambient temperature 3: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature 4: 78 percent / H2S, pyridine / 1.5 h / Ambient temperature 5: diisopropylethylamine / dimethylformamide / 96 h / Ambient temperature 6: aq. NaOH / methanol / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
反应条件
1: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 2: 50percent aq. AcOH / ethyl acetate / Ambient temperature 3: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature View Scheme
参考文献
Itzstein, Mark von; Jin, Betty; Wu, Wen-Yang; Chandler, Malcolm
Carbohydrate Research, 1993 , vol. 244, # 1 p. 181 - 186
反应条件
1: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 2: 50percent aq. AcOH / ethyl acetate / Ambient temperature 3: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature 4: 78 percent / H2S, pyridine / 1.5 h / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
反应条件
barium dihydroxide; water T=90°C; Hydrolysis; 18 h;
参考文献
Wilson, Jennifer C.; Thomson, Robin J.; Dyason, Jeffrey C.; Florio, Pas; Quelch, Kaylene J.; Abo, Samia; Von Itzstein, Mark
Tetrahedron Asymmetry, 2000 , vol. 11, # 1 p. 53 - 73
