(2R,3R,4S)-3-乙酰氨基-4-乙酰氧基-2-((1R,2R)-1,2,3-三乙酰氧基丙基)-3,4-二氢-2H-吡喃-6-羧酸甲酯合成路线 （共 94 条）
反应条件
sodium methylate; sodium hydride Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 116, # 5 p. 1616 - 1634
反应条件
hydrogen bromide; acetic anhydride; acetic acid T=20°C; 1.5 h; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 21 p. 7407 - 7412
反应条件
in 1,2-dichloro-ethane 15 h; Inert atmospherePhotolysis;
参考文献
Kancharla, Pavan K.; Navuluri, Chandrasekhar; Crich, David
Angewandte Chemie - International Edition, 2012 , vol. 51, # 44 p. 11105 - 11109
Angew. Chem., 2012 , vol. 124, # 44 p. 11267 - 11271,5
反应条件
3 A molecular sieve; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate 1.) acetonitrile, 2 h, 2.) acetonitrile, propionitrile, -35 deg C, 3 d; Multistep reaction. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 116, # 5 p. 1616 - 1634
反应条件
methyl sulfenyl bromide; 3 A molecular sieve; silver trifluoromethanesulfonate 1.) acetonitrile, 2 h, 2.) 1,2-dichloroethane, acetonitrile, propionitrile, -50 deg C, 18 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 116, # 5 p. 1616 - 1634
反应条件
methyl sulfenyl bromide; 3 A molecular sieve; silver trifluoromethanesulfonate 1.) acetonitrile, 2 h, 2.) 1,2-dichloroethane, acetonitrile, propionitrile, -50 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 116, # 5 p. 1616 - 1634
反应条件
4 A molecular sieve; silver trifluoromethanesulfonate in N,N-dimethyl-formamide Ambient temperature;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 36, # 3 p. 914 - 919
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile 3 h; Ambient temperature;
参考文献
Synlett, , # 5 p. 479 - 482
反应条件
diethylamine in N,N-dimethyl-formamide T=0 - 20°C; Substitution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 12 p. 1859 - 1866
反应条件
1: 86 percent / pyridine / 14 h / Ambient temperature 2: HCl, acetyl chloride / Ambient temperature 3: acetonitrile / Ambient temperature View Scheme
参考文献
Carbohydrate Research, , vol. 190, p. 317 - 322
