2-氨基-6-甲氧基-3-硝酸吡啶合成路线 （共 17 条）
反应条件
ammonia in methanol T=65°C; 18 h;
参考文献
EISAI CO., LTD.
Patent: WO2005/103049 A1, 2005 ;
Location in patent: Page/Page column 102-103 ;
反应条件
in methanol T=15 - 30°C; 4 - 5 h;
参考文献
JUBILANT ORGANOSYS LIMITED
Patent: US2006/80790 A1, 2006 ;
Location in patent: Page/Page column 3 ;
反应条件
ammonium chloride; potassium tert-butylate in dimethyl sulfoxide
参考文献
Sumitomo Chemical Company, Limited
Patent: US5648496 A1, 1997 ;
反应条件
methoxylamine hydrochloride; potassium tert-butylate; zinc(II) chloride in dimethyl sulfoxide Ambient temperature;
参考文献
Seko, Shinzo; Miyake, Kunihito
Chemical Communications, 1998 , # 15 p. 1519 - 1520
反应条件
methanol; sodium 2 h; Heating / reflux;
参考文献
WO2004/92166 A2, ;
Page 71 ;
WO 2004/092166 A2
反应条件
sulfuric acid; potassium nitrate T=75°C; 2 h;
参考文献
Deady, Leslie W.; Korytsky, Olga L.; Rowe, Jeffrey E.
Australian Journal of Chemistry, 1982 , vol. 35, # 10 p. 2025 - 2034
反应条件
sodium methylate 2 h; Heating;
参考文献
Ohmori; Kubota; Shimizu-Sasamata; Okada; Sakamoto
Journal of Medicinal Chemistry, 1996 , vol. 39, # 6 p. 1331 - 1338
反应条件
1: methanol / 7 h / 140 °C 2: 92 percent / potassium nitrate, concd. H2SO4 / 2 h / 75 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
1: diphenylphosphoryl azide, triethylamine / 26 h / Heating 2: 25percent HBr / 2 h / Ambient temperature 3: methanol / 7 h / 140 °C 4: 92 percent / potassium nitrate, concd. H2SO4 / 2 h / 75 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
反应条件
1: 25percent HBr / 2 h / Ambient temperature 2: methanol / 7 h / 140 °C 3: 92 percent / potassium nitrate, concd. H2SO4 / 2 h / 75 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 35, # 10 p. 2025 - 2034
