3-((输丁基二甲基甲硅烷基)氧)-丙醇合成路线 （共 25 条）
参考文献
Tetrahedron Letters, , vol. 39, # 23 p. 3919 - 3922
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane T=25°C; 3 h;
参考文献
Fournier-Nguefack, Christelle; Lhoste, Paul; Sinou, Denis
Journal of Chemical Research, Miniprint, 1998 , # 3 p. 614 - 634
反应条件
thionyl chloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78 - 20°C; Swern oxidation;
参考文献
Kim, Youngsoon; Fuchs, Philip L.
Organic Letters, 2007 , vol. 9, # 13 p. 2445 - 2448
反应条件
4-methylmorpholine N-oxide; silica gel in dichloromethane; acetonitrile
参考文献
Gong, Leyi; Grupe, Andrew; Peltz, Gary Allen
Patent: US2002/52397 A1, 2002 ;
US 20020052397 A1
反应条件
triethylamine in dichloromethane; dimethyl sulfoxide
参考文献
IGEN International, Inc.
Patent: US6258360 B1, 2001 ;
反应条件
1: dimethyl sulfoxide; oxalyl chloride; triethylamine / CH2Cl2 / -78 - 15 °C 2: 4.5 g / tetrahydrofuran / 0 °C View Scheme
参考文献
Nomura, Izumi; Mukai, Chisato
Organic letters, 2002 , vol. 4, # 24 p. 4301 - 4304
反应条件
1: 87 percent / pyridinium chlorochromate/basic alumina / CH2Cl2 / 1 h / 20 °C 2: N-tosyl-D-phenylalanine; BH3*THF / tetrahydrofuran; CH2Cl2 / 1.5 h / -96 - -78 °C View Scheme
参考文献
Storer, R. Ian; Takemoto, Toshiyasu; Jackson, Philip S.; Brown, Dearg S.; Baxendale, Ian R.; Ley, Steven V.
Chemistry - A European Journal, 2004 , vol. 10, # 10 p. 2529 - 2547
反应条件
1: 1) ClCO-COCl, DMSO, 2) NEt3 / 1) CH2Cl2, -70 deg C, 2) -30 to 0 deg C 2: 80 percent / benzene / 5 h / Heating View Scheme
参考文献
Cardani, Silvia; De Toma, Carlo; Gennari, Cesare; Scolastico, Carlo
Tetrahedron, 1992 , vol. 48, # 27 p. 5557 - 5564
反应条件
1: 92 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 16 h / Ambient temperature 2: 84 percent / N-methylhydrazine / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Harnden; Wyatt; Boyd; Sutton
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 187 - 196
反应条件
1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C / Inert atmosphere 2: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 1 h 3: N-(1-chloro-2-methylprop-1-enyl)-N,N-dimethylamine / dichloromethane / 1 h / Inert atmosphere View Scheme
参考文献
Qi, Jun; Blanden, Adam R.; Bane, Susan; Kingston, David G.I.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 17 p. 5247 - 5254
