1-甲氧基-4-苯基乙炔苯合成路线 （共 169 条）
反应条件
dichloro bis(acetonitrile) palladium(II); nonafluoro-n-butanesulfonyl fluoride; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=60°C; Sonogashira Cross-Coupling; 5 h; Inert atmosphere;
参考文献
Ikawa, Takashi; Saito, Kozumo; Akai, Shuji
Synlett, 2012 , vol. 23, # 15 p. 2241 - 2246
反应条件
1: t-BuOK / dimethylformamide / 75 °C
2: t-BuOK / dimethylformamide / 75 °C
View Scheme
参考文献
Paventi, Martino; Elce, Edmund; Jackman, Rebecca J.; Hay, Allan S.
Tetrahedron Letters, 1992 , vol. 33, # 43 p. 6405 - 6406
反应条件
1: t-BuOK / dimethylformamide / 75 °C
2: t-BuOK / dimethylformamide / 75 °C
View Scheme
参考文献
Paventi, Martino; Elce, Edmund; Jackman, Rebecca J.; Hay, Allan S.
Tetrahedron Letters, 1992 , vol. 33, # 43 p. 6405 - 6406
反应条件
2: Al2O3 / 1,2-dichloro-benzene / 4 h / Heating
View Scheme
参考文献
Wadsworth, D. H.; Donatelli, B. A.
Synthesis, 1981 , # 4 p. 285 - 286
反应条件
2: Al2O3 / 1,2-dichloro-benzene / 4 h / Heating
View Scheme
参考文献
Wadsworth, D. H.; Donatelli, B. A.
Synthesis, 1981 , # 4 p. 285 - 286
反应条件
2: 75 percent / s-BuLi / diethyl ether / adding of s-BuLi -110 deg C, then after 15 min adding of PhLi and 30 min at 0 deg C
View Scheme
参考文献
Martin, Sophie; Sauvetre, Raymond; Normant, Jean-F.
Tetrahedron Letters, 1982 , vol. 23, # 42 p. 4329 - 4332
反应条件
in 1-methyl-pyrrolidin-2-one
T=80°C; 14 h;
参考文献
Tartaggia, Stefano; De Lucchi, Ottorino; Goossen, Lukas J.
European Journal of Organic Chemistry, 2012 , # 7 p. 1431 - 1438
参考文献
Huggins, John M.; Bergman, Robert G.
Journal of the American Chemical Society, 1981 , vol. 103, # 11 p. 3002 - 3011
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
1: 96 percent / Br2 / CH2Cl2 / 16 h
2: 50 percent / KOtBu / 2-methyl-propan-2-ol / 5 h / 50 °C
View Scheme
参考文献
Pati, Hari N.; Wicks, Martha; Holt Jr., Herman L.; LeBlanc, Regan; Weisbruch, Paul; Forrest, Lori; Lee, Moses
Heterocyclic Communications, 2005 , vol. 11, # 2 p. 117 - 120
