1-甲氧基-4-苯基乙炔苯合成路线 （共 169 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride in 1,2-dichloro-ethane
T=20°C; 20 h; Title compound not separated from byproducts;
参考文献
Kakusawa, Naoki; Tobiyasu, Yoshinori; Yasuike, Shuji; Yamaguchi, Kentaro; Seki, Hiroko; Kurita, Jyoji
Tetrahedron Letters, 2003 , vol. 44, # 47 p. 8589 - 8592
反应条件
aluminum oxide; potassium fluoride; copper(l) iodide; triphenylphosphine; nickel
0.05 h; microwave irradiation;
参考文献
Yan, Jincan; Wang, Zhiyuan; Wang, Lei
Journal of Chemical Research, 2004 , # 1 p. 71 - 73
反应条件
PhCH2Pd(PPh3)2Cl in 1,2-dichloro-ethane
T=20°C; 0.333333 h;
参考文献
Kakusawa, Naoki; Tobiyasu, Yoshinori; Yasuike, Shuji; Yamaguchi, Kentaro; Seki, Hiroko; Kurita, Jyoji
Journal of Organometallic Chemistry, 2006 , vol. 691, # 13 p. 2953 - 2968
反应条件
PhCH2Pd(PPh3)2Cl in 1,2-dichloro-ethane
T=20°C; 0.333333 h;
参考文献
Kakusawa, Naoki; Tobiyasu, Yoshinori; Yasuike, Shuji; Yamaguchi, Kentaro; Seki, Hiroko; Kurita, Jyoji
Journal of Organometallic Chemistry, 2006 , vol. 691, # 13 p. 2953 - 2968
反应条件
1: 58 percent / CuI; NaHCO3 / 1,2-dimethoxy-ethane; H2O / 0.5 h / 20 °C
2: 66 percent / CuI; NaOH / butan-1-ol / 24 h / Heating
View Scheme
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
反应条件
1: 95 percent / KOH
View Scheme
参考文献
Al-Hassan, Mohammed I.
Journal of Organometallic Chemistry, 1990 , vol. 395, # 2 p. 227 - 229
反应条件
1.1: Cl2Ni(1,2-bis(diphenylphosphino)ethane); 1,1-dimethylethylmagnesium chloride / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: diisopropyl-carbodiimide / dichloromethane / 24 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Wardrop, Duncan J.; Komenda, John P.
Organic Letters, 2012 , vol. 14, # 6 p. 1548 - 1551
反应条件
1.1: Jone's reagent
2.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / tetrahydrofuran; hexane / 0.05 h / -98 °C / Inert atmosphere
2.2: 2 h / -98 - -60 °C / Inert atmosphere
2.3: Inert atmosphere
3.1: Cl2Ni(1,2-bis(diphenylphosphino)ethane); 1,1-dimethylethylmagnesium chloride / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
3.2: 20 °C / Inert atmosphere
4.1: diisopropyl-carbodiimide / dichloromethane / 24 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Wardrop, Duncan J.; Komenda, John P.
Organic Letters, 2012 , vol. 14, # 6 p. 1548 - 1551
反应条件
PhCH2Pd(PPh3)2Cl in 1,2-dichloro-ethane
T=80°C; 7 h;
参考文献
Kakusawa, Naoki; Tobiyasu, Yoshinori; Yasuike, Shuji; Yamaguchi, Kentaro; Seki, Hiroko; Kurita, Jyoji
Journal of Organometallic Chemistry, 2006 , vol. 691, # 13 p. 2953 - 2968
反应条件
PhCH2Pd(PPh3)2Cl in 1,2-dichloro-ethane
T=20°C; 0.333333 h;
参考文献
Kakusawa, Naoki; Tobiyasu, Yoshinori; Yasuike, Shuji; Yamaguchi, Kentaro; Seki, Hiroko; Kurita, Jyoji
Journal of Organometallic Chemistry, 2006 , vol. 691, # 13 p. 2953 - 2968
