反应条件
1: 64 percent / AlCl3 / 1,2-dichloro-ethane / 16 h / Ambient temperature 2: 1.) 0.5 M potassium bis(trimethylsilyl)amide / 1.) C6H6, tluene, RT, 5 min, 2.) C6H6, toluene, RT, 3 h 3: 91 percent / KOH / methanol; H2O / 1 h / 70 °C View Scheme
参考文献
Dawson; Jong; Hobbs; Cameron; Chao; Pfahl; Lee -; Shroot
Journal of Medicinal Chemistry, 1995 , vol. 38, # 17 p. 3368 - 3383