1: 10percent aq. HCl / tetrahydrofuran / 4 h / 50 °C 2: pyridinium chlorochromate, aluminum oxide / CH2Cl2 / 8 h / Ambient temperature 3: 30 percent / hydrofluoric acid / acetonitrile; H2O / 8 h / 45 °C View Scheme

1: 77 percent / p-toluenesulfonic acid monohydrate / methanol / 12 h / Ambient temperature 2: 75 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 72 h / Ambient temperature 3: 10percent aq. HCl / tetrahydrofuran / 4 h / 50 °C 4: pyridinium chlorochromate, aluminum oxide / CH2Cl2 / 8 h / Ambient temperature 5: 30 percent / hydrofluoric acid / acetonitrile; H2O / 8 h / 45 °C View Scheme

1: 42 percent / aluminum oxide / toluene / 0.5 h / Heating 2: 77 percent / p-toluenesulfonic acid monohydrate / methanol / 12 h / Ambient temperature 3: 75 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 72 h / Ambient temperature 4: 10percent aq. HCl / tetrahydrofuran / 4 h / 50 °C 5: pyridinium chlorochromate, aluminum oxide / CH2Cl2 / 8 h / Ambient temperature 6: 30 percent / hydrofluoric acid / acetonitrile; H2O / 8 h / 45 °C View Scheme

1: 94 percent / cerium(III) chloride heptahydrate, sodium borohydride / methanol / 0.17 h / Ambient temperature 2: 42 percent / aluminum oxide / toluene / 0.5 h / Heating 3: 77 percent / p-toluenesulfonic acid monohydrate / methanol / 12 h / Ambient temperature 4: 75 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 72 h / Ambient temperature 5: 10percent aq. HCl / tetrahydrofuran / 4 h / 50 °C 6: pyridinium chlorochromate, aluminum oxide / CH2Cl2 / 8 h / Ambient temperature 7: 30 percent / hydrofluoric acid / acetonitrile; H2O / 8 h / 45 °C View Scheme

1: 89 percent / aluminum oxide / benzene / 0.25 h / Heating 2: 94 percent / cerium(III) chloride heptahydrate, sodium borohydride / methanol / 0.17 h / Ambient temperature 3: 42 percent / aluminum oxide / toluene / 0.5 h / Heating 4: 77 percent / p-toluenesulfonic acid monohydrate / methanol / 12 h / Ambient temperature 5: 75 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 72 h / Ambient temperature 6: 10percent aq. HCl / tetrahydrofuran / 4 h / 50 °C 7: pyridinium chlorochromate, aluminum oxide / CH2Cl2 / 8 h / Ambient temperature 8: 30 percent / hydrofluoric acid / acetonitrile; H2O / 8 h / 45 °C View Scheme

暂无反应条件数据

暂无反应条件数据

in acetonitrile T=40°C; 15 h; KineticsProduct distribution;