1,2,3,4-四-O-乙酰基-β-D-葡萄糖醛酸甲酯合成路线 (共 33 条)
反应条件
1: methanol; D-(+)-glucuronic acid-γ-lactone With sodium hydroxide T=20°C; 2 h; 2: acetic anhydride With pyridine T=0 - 20°C; 3 h;
参考文献
TIBOTEC BVBA
Patent: WO2004/58787 A2, 2004 ;
Location in patent: Page 29-30 ;
反应条件
1: methanol; D-(+)-glucuronic acid-γ-lactone; sodium methylate T=20°C; 2: acetic anhydride With perchloric acid Cooling with ice;
参考文献
ACADEMIA SINICA; PRIJOVIC, Zeljko, M.; LEU, Yu-Lin; ROFFLER, Steve, R.
Patent: WO2011/66418 A1, 2011 ;
Location in patent: Page/Page column 23 ;
WO 2011/066418 A1
反应条件
aluminum oxide in acetonitrile T=20°C; 2 h;
参考文献
Tiwari, Pallavi; Misra, Anup Kumar
Carbohydrate Research, 2006 , vol. 341, # 3 p. 339 - 350
反应条件
perchloric acid 18 h; Ambient temperature;
参考文献
Liebigs Annalen der Chemie, , p. 637 - 638
反应条件
tri-n-butyl-tin hydride in toluene 30 h; Heatingvariation of scale and reaction time; practical conversion of a D-glucuronic acid derivative into L-iduronic acid derivative by reductive epimerization (after a photobromination); Product distribution;
参考文献
Carbohydrate Research, , vol. 151, p. 379 - 390
反应条件
sodium acetate 8 h; Yield given;
参考文献
Journal of the American Chemical Society, , vol. 118, # 42 p. 10156 - 10167
反应条件
1: NaOH 2: pyridine View Scheme
参考文献
Carbohydrate Research, , vol. 337, # 21-23 p. 2343 - 2346
反应条件
Ag2CO3 in dichloromethane Ambient temperature;
参考文献
Saito, Setsuo; Sasaki, Yuka; Furumoto, Takako; Sumita, Shigeya; Hinomoto, Tohru
Carbohydrate Research, 1994 , vol. 258, p. 59 - 76
参考文献
Journal of the American Chemical Society, , vol. 77, p. 3915
参考文献
Tosin, Manuela; Murphy, Paul V.
Organic Letters, 2002 , vol. 4, # 21 p. 3675 - 3678