(2S)-(苯甲酰基氨基)(苯基)乙酸合成路线 （共 10 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 24 h; Heating;
参考文献
Berardi; Cellucci; Ferorelli; Franchini; Perrone
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 2 p. 181 - 187
反应条件
1: 63 percent / 4-dimethylaminopyridine / tetrahydrofuran / 3.5 h / Heating 2: 95 percent / NaHCO3 / ethanol / 0.5 h / Heating 3: 65 percent / hansenula polymorpha SC 13865 cells / 48 h / 28 °C / K-phosphate buffer (pH 6.0), glucose View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 9 p. 2069 - 2084
反应条件
sodium periodate; ruthenium(III) chloride polyhydrate in tetrachloromethane; water; acetonitrile
T=20°C; optical yield given as percent ee;
参考文献
Almansa, Raquel; Collados, Juan F.; Guijarro, David; Yus, Miguel
Tetrahedron Asymmetry, 2010 , vol. 21, # 11-12 p. 1421 - 1431
反应条件
potassium hydroxide
1 h;
参考文献
Patel, Ramesh N.; Banerjee, Amit; Howell, Jeffrey M.; McNamee, Clyde G.; Brozozowski, David; et al.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 9 p. 2069 - 2084
反应条件
ruthenium(IV) oxide; sodium periodate; water in tetrachloromethane; acetonitrile
2 h;
参考文献
Alvaro, Giuseppe; Martelli, Gianluca; Savoia, Diego; Zoffoli, Andrea
Synthesis, 1998 , # 12 p. 1773 - 1777
反应条件
in water
T=25°C; 20 h; biosynthesis by lipase from Aspergillus niger (AP); phosphate buffer, pH: 7.6; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Gu, Rui-Lin; Lee, Ik-Soo; Sih, Charles J.
Tetrahedron Letters, 1992 , vol. 33, # 15 p. 1953 - 1956
反应条件
1: Et3N / CH2Cl2 / 3 h
2: 75 percent / NaIO4, RuO2*H2O, H2O / acetonitrile; CCl4 / 2 h
View Scheme
参考文献
Alvaro, Giuseppe; Martelli, Gianluca; Savoia, Diego; Zoffoli, Andrea
Synthesis, 1998 , # 12 p. 1773 - 1777
反应条件
1: 1.) H5IO6, MeNH2, 2.) HCl, H2O / 1.) MeOH, H2O
2: Et3N / CH2Cl2 / 3 h
3: 75 percent / NaIO4, RuO2*H2O, H2O / acetonitrile; CCl4 / 2 h
View Scheme
参考文献
Alvaro, Giuseppe; Martelli, Gianluca; Savoia, Diego; Zoffoli, Andrea
Synthesis, 1998 , # 12 p. 1773 - 1777
反应条件
D-glucose; corn steep liquor; fungus Beauveria bassiana ATCC 7159 in ethanol; water
Hydrolysis; 72 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Holland, Herbert L.; Andreana, Peter R.; Salehzadeh-Asl, Reza; Van Vliet, Aaron; Ihasz, Nancy J.; Brown, Frances M.
Monatshefte fur Chemie, 2000 , vol. 131, # 6 p. 667 - 672
反应条件
(NH4)2S2O8; silver nitrate in water
T=20°C;
参考文献
Huang, Wenhua; Wang, Meiling; Yue, Hong
Synthesis, 2008 , # 9 art. no. F23807SS, p. 1342 - 1344
