1,2-bis (triphenylphosphino)ethane tetrabromide in dichloromethane T=23°C; 2 h;

1: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr 2: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C View Scheme

1: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 12 h, 2.) THF, reflux, 18 h 2: 99 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 2 h / 23 °C 3: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 10 h, 2.) THF, 23 deg C, 2 h 4: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr 5: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C View Scheme

1: 94 percent / PBr3, pyridine / diethyl ether / 3 h / -30 - 23 °C 2: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 12 h, 2.) THF, reflux, 18 h 3: 99 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 2 h / 23 °C 4: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 10 h, 2.) THF, 23 deg C, 2 h 5: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr 6: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C View Scheme

1: 99 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 2 h / 23 °C 2: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 10 h, 2.) THF, 23 deg C, 2 h 3: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr 4: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C View Scheme

1: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 10 h, 2.) THF, 23 deg C, 2 h 2: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr 3: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C View Scheme