(-)-3-去甲基秋水仙碱合成路线 （共 5 条）
反应条件
in water 24 h; Ambient temperature;
参考文献
Muzaffar, Anjum; Chrzanowska, Maria; Brossi, Arnold
Heterocycles, 1989 , vol. 28, # 1 p. 365 - 372
反应条件
phosphoric acid
T=25°C; 24 h;
参考文献
Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261
反应条件
bacterium IND-B375
24 h;
参考文献
Maier, Ulrich H.; Zenk, Meinhart H.
Tetrahedron Letters, 1997 , vol. 38, # 42 p. 7357 - 7360
反应条件
1: conc. H2SO4 / 2.5 h / 85 - 90 °C
2: K2CO3 / various solvent(s) / 2.5 h / 70 °C
View Scheme
参考文献
Roesner, Manfred; Hsu, Fu-Lian; Brossi, Arnold
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3686 - 3688
反应条件
sulfuric acid
T=85 - 90°C; 2.5 h;
参考文献
Muzaffar, Anjum; Chrzanowska, Maria; Brossi, Arnold
Heterocycles, 1989 , vol. 28, # 1 p. 365 - 372
