4-氟-alpha-(4-氟苯基)-alpha-(三氟甲基)-苯甲醇合成路线 (共 7 条)
反应条件
potassium tert-butylate in tetrahydrofuran T=25°C; 24 h;
参考文献
Billard, Thierry; Langlois, Bernard R.; Blond, Gaelle
European Journal of Organic Chemistry, 2001 , # 8 p. 1467 - 1471
反应条件
cesium fluoride in N,N-dimethyl-formamide T=-10 - 20°C; 6 h;
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 8848 - 8856
参考文献
Journal of the American Chemical Society, , vol. 77, p. 4164,4167
反应条件
in diethyl ether Grignard reaction; ice-bath temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 70, # 6 p. 1403 - 1411
反应条件
1: red phosphorus; iodine; acetic acid 2: ethanolic KOH View Scheme
参考文献
Mechoulam et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 801
参考文献
Kaluszyner,A. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 3588 - 3590
反应条件
phosphorus; iodine; acetic acid
参考文献
Mechoulam et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 801