1-叔丁氧羰基-2,3-二氢吡咯合成路线 （共 24 条）
反应条件
tris(2,4-di-tert-butyl-phenyl) phosphite; hydrogen; [rhodium(I)(carbonyl)2(acetylacetonate)] in toluene T=50°C; P=7500.75 Torr; 4 h; Product distribution; Further Variations:Reagents;
参考文献
McDonald, Richard I.; Wong, Gene W.; Neupane, Ram P.; Stahl, Shannon S.; Landis, Clark R.
Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14027 - 14029
反应条件
1: H2 / HRh(CO)(PPh3)3 (1), (-)-DIPHOL / benzene / 192 h / 52 °C / 25857.4 Torr 2: KMnO4/MgSO4 / acetone 3: diethyl ether View Scheme
参考文献
Becker, Y.; Eisenstadt, A.; Stille, J. K.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2145 - 2151
反应条件
1: H2 / HRh(CO)(PPh3)3 (1), (-)-DIPHOL / benzene / 192 h / 52 °C / 25857.4 Torr 2: KMnO4/MgSO4 / acetone View Scheme
参考文献
Becker, Y.; Eisenstadt, A.; Stille, J. K.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2145 - 2151
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3; (-)-DIPHOL in benzene T=52°C; P=25857.4 Torr; 192 h; Yield given. Title compound not separated from byproducts;
参考文献
Becker, Y.; Eisenstadt, A.; Stille, J. K.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2145 - 2151
反应条件
[rhodium(I)(carbonyl)2(acetylacetonate)]; hydrogen; (R,S)-Binaphos in benzene T=60°C; P=76000 Torr; 72 h; other reagent: (R)-2-(diphenylphosphino)-1,1'-binaphthalen-2'-yl (S)-3,3'-dimethyl-1,1'-binaphthalene-2,2'-diyl phosphite; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Horiuchi, Toshihide; Ohta, Tetsuo; Shirakawa, Eiji; Nozaki, Kyoko; Takaya, Hidemasa
Journal of Organic Chemistry, 1997 , vol. 62, # 13 p. 4285 - 4292
反应条件
1: hydrogen, Rh(acac)(CO)2, (R)-2-(diphenylphosphino)-1,1'-binaphthalen-2'-yl (S)-1,1'-binaphthalene-2,2'-diyl phosphite / benzene / 72 h / 60 °C / 76000 Torr / other reagent: (R)-2-(diphenylphosphino)-1,1'-binaphthalen-2'-yl (S)-3,3'-dimethyl-1,1'-binaphthalene-2,2'-diyl phosphite 2: borane-THF / tetrahydrofuran / 1.) 0 deg C, 2 h, 2.) room temperature, overnight View Scheme
参考文献
Horiuchi, Toshihide; Ohta, Tetsuo; Shirakawa, Eiji; Nozaki, Kyoko; Takaya, Hidemasa
Journal of Organic Chemistry, 1997 , vol. 62, # 13 p. 4285 - 4292
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3; (-)-DIPHOL in benzene T=52°C; P=25857.4 Torr; 192 h; Yield given. Title compound not separated from byproducts;
参考文献
Becker, Y.; Eisenstadt, A.; Stille, J. K.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2145 - 2151
反应条件
[Rh(acac)2(CO)2]; C50H44Cl4N4O4P2; hydrogen in toluene T=40°C; P=15001.5 Torr; 20 h; Inert atmosphereAutoclave; enantioselective reaction;
参考文献
Xu, Kun; Zheng, Xin; Wang, Zhiyong; Zhang, Xumu
Chemistry - A European Journal, 2014 , vol. 20, # 15 p. 4357 - 4362
反应条件
1: H2 / HRh(CO)(PPh3)3 (1), (-)-DIPHOL / benzene / 192 h / 52 °C / 25857.4 Torr 2: KMnO4/MgSO4 / acetone 3: diethyl ether View Scheme
参考文献
Becker, Y.; Eisenstadt, A.; Stille, J. K.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2145 - 2151
反应条件
[Ru(η4-COD)(η3-methylallyl)2]; 2-(dicyclohexylphosphino)-1-(2-methoxyphenyl)-1H-imidazole; hydrogen in toluene T=160°C; P=37503.8 Torr; 24 h; AutoclaveInert atmosphere; Overall yield = 43 percentChromat.; regioselective reaction;
参考文献
Wu, Lipeng; Fleischer, Ivana; Jackstell, Ralf; Profir, Irina; Franke, Robert; Beller, Matthias
Journal of the American Chemical Society, 2013 , vol. 135, # 38 p. 14306 - 14312
