2-(三氟甲基)咪唑并[1,2-a]吡啶合成路线 (共 5 条)
反应条件
1: in 1,4-dioxane; ethanol 2: With triethylamine in 1,4-dioxane; ethanol Reflux;
参考文献
Vilchis-Reyes, Miguel Angel; Zentella, Alejandro; Martinez-Urbina, Miguel Angel; Guzman, Angel; Vargas, Omar; Ramirez Apan, Maria Teresa; Ventura Gallegos, Jose Luis; Diaz, Eduardo
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 379 - 386
反应条件
in ethanol 0.5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 4 p. 1031 - 1034
反应条件
1: 82 percent / CF3COOH / 24 h / Ambient temperature 2: 95 percent / 200 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 26, p. 499 - 506
反应条件
1: 1,2-dichloro-ethane / 2 h / Ambient temperature 2: 1,2-dichloro-ethane / 5 h / Heating View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 73, # 1 p. 83 - 86
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 6 p. 1958 - 1962