4,4,4-三氟-3-羟基-1-苯基-3-(三氟甲基)-1-丁酮合成路线 （共 10 条）
反应条件
pyridine; trifluoroacetic anhydride in diethyl ether T=0°C; 1 h;
参考文献
Burger, Klaus; Helmreich, Brigitte
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 219 - 226
反应条件
hydrogen; palladium on activated charcoal in di-isopropyl ether T=40°C; P=7500.75 Torr; 12 h;
参考文献
Komata, Takeo; Matsunaga, Kei; Hirotsu, Yoshiki; Akiba, Shinya; Ogura, Katsuyuki
Journal of Fluorine Chemistry, 2007 , vol. 128, # 8 p. 902 - 909
反应条件
T=160°C; 120 h; Sealed autoclave;
参考文献
TOTAL PETROCHEMICALS RESEARCH FELUY
Patent: EP1900722 A1, 2008 ;
Location in patent: Page/Page column 4-5 ;
反应条件
in dichloromethane
T=20°C; 1440 h;
参考文献
Paleta, Oldrich; Dolensky, Bohumil; Palecek, Jiri; Kvicala, Jaroslav
Journal of Fluorine Chemistry, 2014 , vol. 157, p. 1 - 11
反应条件
tin(IV) chloride in tetrahydrofuran
T=-35 - -30°C;
参考文献
Ishihara, Takashi; Shinjo, Hiroshi; Inoue, Yoshihisa; Ando, Teiichi
Journal of Fluorine Chemistry, 1983 , vol. 22, p. 1 - 20
反应条件
hydrogenchloride in methanol
4 h; Ambient temperature;
参考文献
Burger, Klaus; Helmreich, Brigitte
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 219 - 226
反应条件
1: in hexane
T=20°C; 24 h;
2: With hydrogenchloride in hexane
T=20°C; 0.5 h;
参考文献
Funabiki; Isomura; Yamaguchi; Hashimoto; Matsunaga; Shibata; Matsui
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 20 p. 2578 - 2582
反应条件
1: 90 percent / CH2Cl2
2: 91 percent / aq. HCl / methanol / 4 h / Ambient temperature
View Scheme
参考文献
Burger, Klaus; Helmreich, Brigitte
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 219 - 226
反应条件
1: diethyl ether
2: Hg(OAc)2, H2SO4
View Scheme
参考文献
Knunyants,I.L. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1960 , # 4 p. 647 - 653
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1960 , # 4 p. 686 - 692
反应条件
sulfuric acid; mercury(II) diacetate
参考文献
Knunyants,I.L. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1960 , # 4 p. 647 - 653
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1960 , # 4 p. 686 - 692
