2,4-二羟基-5-甲氧基苯乙酮合成路线 （共 11 条）
反应条件
boron trifluoride diethyl etherate
T=70°C; Fries rearrangement;
参考文献
Zhang, Qingzhi; Botting, Nigel P.
Tetrahedron, 2004 , vol. 60, # 52 p. 12211 - 12216
参考文献
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
Patent: WO2004/69774 A2, 2004 ;
Location in patent: Page 89 ;
反应条件
hydrogenchloride; diethyl ether; zinc(II) chloride
und Erhitzen des Reaktionsprodukts mit Wasser;
参考文献
Daly et al.
Biochemistry, 1965 , vol. 4, p. 2513
反应条件
1.2: MCPBA / CH2Cl2
1.3: aq. NaHCO3 / ethanol
2.1: BF3*Et2O / 70 °C
View Scheme
参考文献
Zhang, Qingzhi; Botting, Nigel P.
Tetrahedron, 2004 , vol. 60, # 52 p. 12211 - 12216
反应条件
hydrogenchloride; acetic acid
参考文献
Laumas et al.
Proceedings - Indian Academy of Sciences, Section A, 1957 , vol. 46, p. 343,346
反应条件
aluminium trichloride
参考文献
Ballio; Almirante
Ricerca Scientifica, 1950 , vol. 20, p. 829
反应条件
1: K2S2O8; aqueous KOH; pyridine / Erhitzen des Reaktionsprodukts mit wss.HCl und Na2SO3
2: K2CO3; acetone
3: concentrated HCl; acetic acid
View Scheme
参考文献
Laumas et al.
Proceedings - Indian Academy of Sciences, Section A, 1957 , vol. 46, p. 343,346
反应条件
1: K2CO3; acetone
2: concentrated HCl; acetic acid
View Scheme
参考文献
Laumas et al.
Proceedings - Indian Academy of Sciences, Section A, 1957 , vol. 46, p. 343,346
反应条件
potassium carbonate in acetone
5 h; Heating / reflux;
参考文献
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
Patent: WO2004/69774 A2, 2004 ;
Location in patent: Page 89 ;
反应条件
1: 0.45 g / 90percent orthophosphoric acid / petroleum ether / 12 h / 30 - 35 °C
2: 0.45 g / DDQ / benzene / 60 h / Heating
View Scheme
参考文献
Ahluwalia, V. K.; Arora, K. K.; Manchanda, Saroj
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 11 p. 1039 - 1040
