3-甲氧基-N,N-二甲基-苯甲酰胺合成路线 （共 10 条）
反应条件
tert.-butylhydroperoxide; hydrogen bromide in methanol 6 h; Heating;
参考文献
Barhate, Nivrutti B.; Gajare, Anil S.; Wakharkar, Radhika D.; Bedekar, Ashutosh V.
Tetrahedron, 1999 , vol. 55, # 36 p. 11127 - 11142
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1.) 0 deg C; 2.) rt, 30 min, reflux 2h;
参考文献
Yamagiwa, Yoshiro; Ohashi, Kinji; Sakamoto, Yoshitaka; Hirakawa, Shinji; Kamikawa, Tadao; Kubo, Isao
Tetrahedron, 1987 , vol. 43, # 15 p. 3387 - 3394
反应条件
tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide in trichloroethane, 1,1,2-; water
T=90°C; 12 h;
参考文献
Li, Huamin; Xie, Jin; Xue, Qicai; Cheng, Yixiang; Zhu, Chengjian
Tetrahedron Letters, 2012 , vol. 53, # 48 p. 6479 - 6482,4
反应条件
1: 3-methoxybromobenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: N,N-dimethyl-formamide in tetrahydrofuran; hexane
T=-78 - 20°C; 2 h;
3: methanol Further stages;
参考文献
Ushijima, Sousuke; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2012 , vol. 68, # 24 p. 4701 - 4709
反应条件
tert.-butylhydroperoxide in acetonitrile
T=80°C; 24 h;
参考文献
Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432
反应条件
sodium methylate; nickel diacetate in 1,4-dioxane
T=110°C;
参考文献
Ju, Jinhun; Jeong, Miso; Moon, Jeongju; Hyun, Min Jung; Lee, Sunwoo
Organic Letters, 2007 , vol. 9, # 22 p. 4615 - 4618
反应条件
bis(di-tert-butylphosphinous acid)PdCl2 in acetonitrile
T=50°C; 24 h;
参考文献
Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432
反应条件
nickel in ethanol
3 h; Reflux;
参考文献
Flemming, Jonathan P.; Berry, Malcolm B.; Brown, John M.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 7 p. 1215 - 1221
反应条件
1: thionyl chloride / 1 h / Ambient temperature
2: CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Yamagiwa, Yoshiro; Ohashi, Kinji; Sakamoto, Yoshitaka; Hirakawa, Shinji; Kamikawa, Tadao; Kubo, Isao
Tetrahedron, 1987 , vol. 43, # 15 p. 3387 - 3394
参考文献
Somin,I.N.; Germanguz,E.A.
Journal of Organic Chemistry USSR (English Translation), 1969 , vol. 5, p. 1727 - 1730
Zhurnal Organicheskoi Khimii, 1969 , vol. 5, p. 1780 - 1783
