1,3,5-三(三氟甲基)苯合成路线 （共 24 条）
参考文献
Industrial and Engineering Chemistry, , vol. 39, p. 393
反应条件
T=168°C; 192 h; Product distribution;
参考文献
Journal of Fluorine Chemistry, , vol. 47, # 2 p. 283 - 299
反应条件
triethylsilane; C24BF20(1-)*C18F16P(1+) T=20°C; 24 h;
参考文献
Caputo, Christopher B.; Hounjet, Lindsay J.; Dobrovetsky, Roman; Stephan, Douglas W.
Science, 2013 , vol. 341, # 6152 p. 1374 - 1377
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in diethyl ether T=-25°C; 2 h;
参考文献
Schlosser, Manfred; Mongin; Porwisiak, Jacek; Dmowski, Wojciech; Bueker, Heinz H.; Nibbering, Nico M. M.
Chemistry - A European Journal, 1998 , vol. 4, # 7 p. 1281 - 1286
反应条件
1: With trifluorormethanesulfonic acid in chloroform 4 h; Inert atmosphere; 2: With water in chloroform Inert atmosphere;
参考文献
Kethe, Anila; Tracy, Adam F.; Klumpp, Douglas A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 12 p. 4545 - 4549
反应条件
1: 75 percent / n-BuLi / hexane; diethyl ether / 1.) -5 deg C, 2.) 2 h 2: 85 percent / PCl5 / CCl4 / 1 h / Heating View Scheme
参考文献
Filler, Robert; Gnandt, William K.; Chen, Wei; Lin, Shan
Journal of Fluorine Chemistry, 1991 , vol. 52, # 1 p. 99 - 105
反应条件
1: 75 percent / n-BuLi / hexane; diethyl ether / 1.) -5 deg C, 2.) 2 h 2: 85 percent / PCl5 / CCl4 / 1 h / Heating 3: 90 percent / NH3 / acetone / 12 h / Heating 4: 75 percent / Br2, aq. KOH / 12 h / 0 °C View Scheme
参考文献
Ahlemann, Jens-T; Roesky, Herbert W.; Noltemeyer, Mathias; Schmidt, Hans-G.; Markovsky, Leonid N.; Shermolovich, Yuri G.
Journal of Fluorine Chemistry, 1998 , vol. 87, # 1 p. 87 - 90
反应条件
1: 1.) 1.6 N butyllithium; 2.) PCl3 / 1.) Et2O, hexane, r.t., 2 h; 2.) Et2O, r.t. 2: 69 percent / DBU / tetrahydrofuran / 0 °C View Scheme
参考文献
Scholz, Mario; Roesky, Herbert W.; Stalke, Dietmar; Keller, Klaus; Edelmann, Frank T.
Journal of Organometallic Chemistry, 1989 , vol. 366, p. 73 - 86
反应条件
sulfur; n-butyllithium in diethyl ether; hexane
1 h;
参考文献
Carr, G. E.; Chambers, R. D.; Holmes, T. F.; Parker, P. G.
Journal of Organometallic Chemistry, 1987 , vol. 325, p. 13 - 24
反应条件
1: 1,3,5-tris(trifluoromethyl)benzene With n-butyllithium in diethyl ether
T=-78°C;
2: germanium tetrachloride in hexane
T=-78°C;
参考文献
Xue, Bao Yu; Dillon, Keith B.
Helvetica Chimica Acta, 2013 , vol. 96, # 6 p. 1078 - 1084
