4-乙氧基-4’-联二苯羧酸合成路线 （共 5 条）
反应条件
sodium hydroxide in ethylene glycol
参考文献
Merck
Patent: FR2288732DE2450088 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 46219
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH
2: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH
View Scheme
参考文献
Klein, Scott I.; Czekaj, Mark; Gardner, Charles J.; Guertin, Kevin R.; Cheney, Daniel L.; Spada, Alfred P.; Bolton, Scott A.; Brown, Karen; Colussi, Dennis; Heran, Christopher L.; Morgan, Suzanne R.; Leadley, Robert J.; Dunwiddie, Christopher T.; Perrone, Mark H.; Chu, Valeria
Journal of Medicinal Chemistry, 1998 , vol. 41, # 4 p. 437 - 450
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH
2: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH
View Scheme
参考文献
Klein, Scott I.; Czekaj, Mark; Gardner, Charles J.; Guertin, Kevin R.; Cheney, Daniel L.; Spada, Alfred P.; Bolton, Scott A.; Brown, Karen; Colussi, Dennis; Heran, Christopher L.; Morgan, Suzanne R.; Leadley, Robert J.; Dunwiddie, Christopher T.; Perrone, Mark H.; Chu, Valeria
Journal of Medicinal Chemistry, 1998 , vol. 41, # 4 p. 437 - 450
反应条件
bis-triphenylphosphine-palladium(II) chloride; n-butyllithium; diisobutylaluminium hydride; zinc(II) chloride
Multistep reaction;
参考文献
Klein, Scott I.; Czekaj, Mark; Gardner, Charles J.; Guertin, Kevin R.; Cheney, Daniel L.; Spada, Alfred P.; Bolton, Scott A.; Brown, Karen; Colussi, Dennis; Heran, Christopher L.; Morgan, Suzanne R.; Leadley, Robert J.; Dunwiddie, Christopher T.; Perrone, Mark H.; Chu, Valeria
Journal of Medicinal Chemistry, 1998 , vol. 41, # 4 p. 437 - 450
参考文献
Gray et al.
Journal of the Chemical Society, 1955 , p. 1412,1414, 1418, 1420
