2-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯合成路线

参考文献

ELI LILLY AND COMPANY; BASTIAN, Jolie, Anne; CLAY, Julia, Marie; COHEN, Jeffrey, Daniel; HIPSKIND, Philip, Arthur; LOBB, Karen, Lynn; SALL, Daniel, Jon; WILSON (NEE TAKAKUWA), Takako; THOMPSON, Michelle, Lee
Patent: WO2010/56588 A1, 2010 ;
Location in patent: Page/Page column 13 ;

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141860-78-8乙基3-氨基-4,4,4-三氟-2-丁烯酸酯+

2757-23-5氯羰基亚磺酰氯

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参考文献

US4251261 A1, ;

72850-53-42-氧代-4-(三氟甲基)-2,3-二氢-1,3-噻唑-5-甲醛

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

参考文献

Liu, Chang-Ling; Li, Miao; Chi, Hui-Wei; Hou, Chun-Qing; Li, Zheng-Ming
Journal of Fluorine Chemistry, 2006 , vol. 127, # 6 p. 796 - 799

372-29-23-氨基-4,4,4-三氟巴豆酸乙酯

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

参考文献

Journal of Heterocyclic Chemistry, , vol. 22, p. 1621 - 1630

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

106203-24-14-三氟甲基-5-噻唑甲酸乙酯

参考文献

Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630

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72850-61-42-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID

参考文献

Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

72850-64-7解草胺

参考文献

Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630

110-91-8吗啉+

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

338392-97-52-吗啉-4-基-4-(三氟甲基)-1,3-噻唑-5-羧酸乙酯

参考文献

ELI LILLY AND COMPANY; BASTIAN, Jolie, Anne; CLAY, Julia, Marie; COHEN, Jeffrey, Daniel; HIPSKIND, Philip, Arthur; LOBB, Karen, Lynn; SALL, Daniel, Jon; WILSON (NEE TAKAKUWA), Takako; THOMPSON, Michelle, Lee
Patent: WO2010/56588 A1, 2010 ;
Location in patent: Page/Page column 13 ;

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

72850-71-6

参考文献

Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630