3,4-二甲氧基-2-甲基吡啶-N-氧化物合成路线 （共 15 条）
反应条件
in methanol T=40°C; 16 h;
参考文献
Maharvi, Ghulam M.; Bharucha, Adil E.; Fauq, Abdul H.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2808 - 2811
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane 4 h; Ambient temperature;
参考文献
Kuhler; Fryklund; Bergman; Weilitz; Lee; Larsson
Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4906 - 4916
反应条件
sodium methylate T=40°C; 16 h;
参考文献
Kohl; Sturm; Senn-Bilfinger; Simon; Kruger; Schaefer; Rainer; Figala; Klemm
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1049 - 1057
反应条件
in methanol; toluene; Petroleum ether
反应条件
sodium methylate 18 h;
参考文献
Kohl; Sturm; Senn-Bilfinger; Simon; Kruger; Schaefer; Rainer; Figala; Klemm
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1049 - 1057
反应条件
1: 85 percent / POCl3 / 10 h / Heating 2: NaOMe / 10 h / Heating 3: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: NaOMe / 10 h / Heating 2: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: 68 percent / K2CO3 / acetone / 19 h / Heating 2: 77 percent / conc. ammonia / 3 h / 110 °C 3: 85 percent / POCl3 / 10 h / Heating 4: NaOMe / 10 h / Heating 5: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: 77 percent / conc. ammonia / 3 h / 110 °C 2: 85 percent / POCl3 / 10 h / Heating 3: NaOMe / 10 h / Heating 4: 98 percent / 84percent m-CPBA / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: 58 percent / 98percent HNO3 / acetic acid / 33 h / 80 °C 2: 88 percent / NaOMe / 16 h / 40 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 6 p. 1049 - 1057
