甲基(E)-3-[4-羟基-3-(3-甲基丁-2-烯基)苯基]丙-2-烯酸酯合成路线 （共 16 条）
反应条件
palladium diacetate; triethylamine; tris-(o-tolyl)phosphine in N,N-dimethyl-formamide
T=100°C; Heck reaction; 40 h; Inert atmosphere;
参考文献
Lykakis, Ioannis N.; Efe, Christina; Gryparis, Charis; Stratakis, Manolis
European Journal of Organic Chemistry, 2011 , # 12 p. 2334 - 2338
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride in acetonitrile
T=100°C; 14 h;
参考文献
Bates, Roderick W.; Gabel, Christine J.; Ji, Jianhua; Rama-Devi, Thota
Tetrahedron, 1995 , vol. 51, # 30 p. 8199 - 8212
反应条件
potassium carbonate in methanol
参考文献
Bates, Roderick W.; Gabel, Christine J.; Ji, Jianhua; Rama-Devi, Thota
Tetrahedron, 1995 , vol. 51, # 30 p. 8199 - 8212
反应条件
in diethyl ether
T=0°C; 2 h;
参考文献
Bisogno, Fabricio; Mascoti, Laura; Sanchez, Cecilia; Garibotto, Francisco; Giannini, Fernando; Kurina-Sanz, Marcela; Enriz, Ricardo
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 26 p. 10635 - 10640
反应条件
1: 57 percent / NaH / toluene
2: 78 percent / Et3N, DMAP / CH2Cl2
3: 60 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 24 h / 100 °C
4: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: 68 percent / NaH / toluene
2: 91 percent / Et3N, DMAP / CH2Cl2
3: 96 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 20 h / Heating
4: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: 57 percent / NaH / toluene
2: 78 percent / Et3N, DMAP / CH2Cl2
3: 60 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 24 h / 100 °C
4: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: 78 percent / Et3N, DMAP / CH2Cl2
2: 60 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 24 h / 100 °C
3: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: 91 percent / Et3N, DMAP / CH2Cl2
2: 96 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 20 h / Heating
3: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
反应条件
1: 60 percent / (o-tol)3P, Et3N / Pd(OAc)2 / toluene / 24 h / 100 °C
2: 89 percent / K2CO3 / methanol
View Scheme
参考文献
Bates; Gabel
Tetrahedron Letters, 1993 , vol. 34, # 22 p. 3547 - 3550
