2-(三氟甲基)苯并苯酮合成路线 （共 19 条）
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2; oxygen in toluene T=20 - 165°C; P=760.051 Torr; 24 h;
参考文献
Rao, Honghua; Yang, Luo; Shuai, Qi; Li, Chao-Jun
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 10 p. 1701 - 1706
反应条件
chromium(VI) oxide; sulfuric acid T=0°C;
参考文献
Brown, Eric; Chevalier, Christelle; Huet, Francois; Grumelec, Christelle Le; Leze, Antoine; Touet, Joel
Tetrahedron: Asymmetry, 1994 , vol. 5, # 7 p. 1191 - 1194
反应条件
1: 2-bromo-α,α,α-trifluorotoluene With diisobutyl-aluminum chloride; diisobutylaluminium hydride; magnesium; lithium chloride in tetrahydrofuran; n-heptane T=25°C; 2: benzoyl chloride With CuCN*2LiCl in tetrahydrofuran; n-heptane T=-10 - 25°C; 3 h;
参考文献
Gao, Hongjun; Knochel, Paul
Synlett, 2009 , # 8 p. 1321 - 1325
反应条件
palladium diacetate; potassium carbonate in methoxybenzene T=140°C; Suzuki coupling; 12 h;
参考文献
Jafarpour, Farnaz; Rashidi-Ranjbar, Parviz.; Kashani, Asieh Otaredi
European Journal of Organic Chemistry, 2011 , # 11 p. 2128 - 2132
反应条件
copper; isopentyl nitrite in acetonitrile T=0 - 15°C; Sandmeyer Reaction; 8 h; Schlenk techniqueInert atmosphere;
参考文献
Dai, Jian-Jun; Fang, Chi; Xiao, Bin; Yi, Jun; Xu, Jun; Liu, Zhao-Jing; Lu, Xi; Liu, Lei; Fu, Yao
Journal of the American Chemical Society, 2013 , vol. 135, # 23 p. 8436 - 8439
反应条件
trifluorormethanesulfonic acid Friedel-Crafts type reaction; 4 h; Inert atmosphere;
参考文献
Kethe, Anila; Tracy, Adam F.; Klumpp, Douglas A.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 12 p. 4545 - 4549
反应条件
1: (trifluoromethyl)-trimethylsilane With copper(I) isothiocyanate; caesium carbonate in acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: 2-benzoylbenzenediazonium tetrafluoroborate in acetonitrile T=20°C; Sandmeyer Reaction; 16 h; Inert atmosphere;
参考文献
Danoun, Gregory; Bayarmagnai, Bilguun; Gruenberg, Matthias F.; Goossen, Lukas J.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 31 p. 7972 - 7975
Angew. Chem., 2013 , vol. 125, # 31 p. 8130 - 8133
反应条件
isobutyramide; copper T=100°C; 8 h;
参考文献
Journal of Fluorine Chemistry, , vol. 50, # 3 p. 411 - 426
反应条件
1: 85 percent / diethyl ether 2: 92 percent / CrO3, H2SO4 / 0 °C View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 5, # 7 p. 1191 - 1194
反应条件
1: 85 percent / diethyl ether 2: 92 percent / CrO3, H2SO4 / 0 °C View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 5, # 7 p. 1191 - 1194
