2-(三氟甲基)二苯甲醇合成路线 （共 11 条）
反应条件
sodium hydroxide; zinc in ethanol 2 h; Heating;
参考文献
Bulletin de la Societe Chimique de France, , p. 587 - 593
反应条件
1: 2-bromo-α,α,α-trifluorotoluene With iodine; magnesium in tetrahydrofuran T=100°C; 1 h; microwave irradiation; 2: benzaldehyde in tetrahydrofuran T=100°C; Grignard reaction; 0.5 h; microwave irradiation;
参考文献
Synlett, , # 10 art. no. D06705ST, p. 1596 - 1600
反应条件
1: 1-iodo-2-(trifluoromethyl)benzene With manganese in tetrahydrofuran T=0°C; 2: benzaldehyde in tetrahydrofuran T=25°C;
参考文献
Tetrahedron, , vol. 57, # 42 p. 8807 - 8815
反应条件
1: 3,4,5-trimethoxyphenylboronic acid With TMG in toluene T=20°C; 2 h; Inert atmosphere; 2: α,α,α-trifluoro-o-tolualdehyde in toluene T=20°C; 8 h; Inert atmosphere;
参考文献
Synlett, , # 3 p. 495 - 499
反应条件
n-butyl-magnesium bromide in diethyl ether T=0°C; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 56, # 7 p. 2573 - 2575
参考文献
Tetrahedron: Asymmetry, , vol. 5, # 7 p. 1191 - 1194
反应条件
in diethyl ether T=0°C; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 56, # 7 p. 2573 - 2575
反应条件
1: AlCl3 / 2 h / 0 - 2 °C 2: Zn, NaOH / aq. ethanol / 2 h / Heating View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 587 - 593
反应条件
1: SOCl2 2: AlCl3 / 2 h / 0 - 2 °C 3: Zn, NaOH / aq. ethanol / 2 h / Heating View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 587 - 593
反应条件
in diethyl ether Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 4 p. 1378 - 1383
