4,4-二甲氧基二苯基甲烷合成路线 （共 148 条）
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in water; N,N-dimethyl-formamide
T=153°C; 12 h;
参考文献
Wang, Xing; Liu, Lian-Hua; Shi, Jin-Hua; Peng, Ji; Tu, Hai-Yang; Zhang, Ai-Dong
European Journal of Organic Chemistry, 2013 , # 30 p. 6870 - 6877
反应条件
ammonium formate; palladium on activated charcoal in methanol
3 h; Ambient temperature;
参考文献
Balicki, Roman
Gazzetta Chimica Italiana, 1992 , vol. 122, # 3 p. 133 - 134
反应条件
NOBF4 in dichloromethane
T=0°C; 4 h;
参考文献
Rathore, Rajendra; Kochi, Jay K.
Acta Chemica Scandinavica, 1998 , vol. 52, # 1 p. 114 - 130
反应条件
triethylsilane; trifluorormethanesulfonic acid in chloroform
T=20°C; 0.75 h;
参考文献
Waterlot; Couturier; De Backer; Rigo
Canadian Journal of Chemistry, 2000 , vol. 78, # 9 p. 1242 - 1246
反应条件
1: (4-methoxyphenyl)methanol With n-butyllithium; chloro-diphenylphosphine in tetrahydrofuran
2: With methyl iodide in tetrahydrofuran
T=20°C; 1 h;
3: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=20°C; 1 h;
参考文献
Shintou, Taichi; Kikuchi, Wataru; Mukaiyama, Teruaki
Chemistry Letters, 2003 , vol. 32, # 8 p. 676 - 677
反应条件
1: 1.) Mg / diethyl ether / 18 h / Heating
2: 87 percent / hydrogen / 5 percent Pd/C (70 percent perchloric acid) / methanol / 18 h / 1520 Torr / Ambient temperature
View Scheme
参考文献
Streitwieser, Andrew Jr.; Vorpagel, Erich R.; Chen, Chia-Chung
Journal of the American Chemical Society, 1985 , vol. 107, # 24 p. 6970 - 6975
参考文献
Sun, Gaojun; Wang, Zhiyong
Tetrahedron Letters, 2008 , vol. 49, # 33 p. 4929 - 4932
反应条件
chloro-trimethyl-silane; zinc(II) chloride in dichloromethane
T=20°C; Friedel Crafts alkylation; 3 h;
参考文献
Liu, Cong-Rong; Li, Man-Bo; Yang, Cui-Feng; Tian, Shi-Kai
Chemistry - A European Journal, 2009 , vol. 15, # 3 p. 793 - 797
反应条件
1: With Pd0(tris(tert-butyl)phosphine)2; potassium hydroxide in 1,4-dioxane; water
T=20°C; Suzuki-Miyaura Coupling; 12 h; Inert atmosphere;
2: With potassium hydroxide in 1,4-dioxane; water
T=60°C; Suzuki-Miyaura Coupling; 5 h; Inert atmosphere;
参考文献
Endo, Kohei; Ishioka, Takafumi; Ohkubo, Takahiro; Shibata, Takanori
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7223 - 7231
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; diphenylcyclohexyl phosphine in 1,4-dioxane
T=40°C; 24 h; Inert atmosphereGlovebox;
参考文献
Maity, Prantik; Shacklady-Mcatee, Danielle M.; Yap, Glenn P. A.; Sirianni, Eric R.; Watson, Mary P.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 280 - 285
