1,1,1,3,3,3-hexamethyl-disilazane in dichloromethane T=-20 - -18°C; Product distribution; Further Variations:Reagents;

4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=0 - 20°C; 2 h; Inert atmosphere;

4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=0 - 20°C; 10 h;

1: 97 percent / 10N KOH / ethanol / 20 h / Heating 2: 75 percent / NEt3 / diethyl ether / 1.) 0 deg C, 4 h, 2.) 20 deg C, 12 h View Scheme

1: L-Selectridereg; / tetrahydrofuran / 2 h / 0 °C / |Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 20 °C / |Inert atmosphere 3: triethylamine; 4-(N,N-dimethlyamino)pyridine View Scheme