2-氯-4-甲基-1,3-噻唑-5-甲酸乙酯合成路线 (共 15 条)
反应条件
trichlorophosphate Heating;
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
反应条件
hydrogenchloride; Copper(I)chloride in water; acetonitrile
参考文献
Dow AgroSciences LLC
Patent: US6413997 B1, 2002 ;
反应条件
hydrogenchloride; Copper(I)chloride in acetonitrile
参考文献
Dow AgroSciences LLC
Patent: US6096898 A1, 2000 ;
反应条件
1: 60 percent / chlorobenzene / 2 h / 80 - 135 °C 2: 91 percent / POCl3 / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, p. 1621 - 1630
反应条件
(i) HNO3, aq. H3PO4, (ii) NaNO2, (iii) NaCl, CuSO4; Multistep reaction;
参考文献
Journal of medicinal chemistry, , vol. 12, # 3 p. 553 - 553
反应条件
2: POCl3 View Scheme
参考文献
Proceedings - Indian Academy of Sciences, Section A, , # 22 p. 362,376
参考文献
Yakugaku Zasshi, , vol. 79, p. 1155,1157
Chem.Abstr., , p. 3382
参考文献
Yakugaku Zasshi, , vol. 79, p. 1155,1157
Chem.Abstr., , p. 3382
参考文献
Wohmann
Justus Liebigs Annalen der Chemie, 1890 , vol. 259, p. 298
反应条件
lithium hexamethyldisilazane in tetrahydrofuran T=-40°C; Claisen condensation; 0.333333 h; Inert atmosphere;
参考文献
Venkat Ragavan; Vijayakumar; Rajesh; Palakshi Reddy; Karthikeyan; Suchetha Kumari
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4193 - 4197