反应条件
1: 88 percent / tetrahydrofuran / 4 h / Ambient temperature
2: 1.) sec-BuLi / 1.) THF, cyclohexane, -30 deg C, 10 min, 2.) THF, cyclohexane, from -60 to -30 deg C, 0.5 h
3: 92 percent / CF3COOH / CH2Cl2 / 0.5 h / 0 - 20 °C
4: 98 percent / H2 / Pd(OH)2 / ethyl acetate / 12 h / 2327.2 Torr
5: 1.) CF3COOH, 2.) aq. NaHCO3 / 1.) CH2Cl2, RT, 2 h
View Scheme
参考文献
Clark; Jahangir; Langston
Canadian Journal of Chemistry, 1994 , vol. 72, # 1 p. 23 - 30
