4-甲基-2-甲硫基嘧啶-5-甲酸乙酯合成路线 （共 16 条）
参考文献
Chi; Wu
Huaxue Xuebao, 1957 , vol. 23, p. 145,150
Scientia Sinica (English Edition), 1957 , vol. 6, p. 853
Chem.Abstr., 1958 , p. 14626
参考文献
Chi; Wu
Huaxue Xuebao, 1957 , vol. 23, p. 145,150
Scientia Sinica (English Edition), 1957 , vol. 6, p. 853
Chem.Abstr., 1958 , p. 14626
反应条件
1: With sodium hydroxide; ethanol; water T=0 - 20°C; 2 h; 2: With hydrogenchloride in water
参考文献
KUMIAI CHEMICAL INDUSTRY CO., LTD.; Ihara Chemical Industry Co., Ltd.
Patent: EP1439169 A1, 2004 ;
Location in patent: Page 97 ;
反应条件
1: 80 percent / 2 N NaOH / Ambient temperature 2: 76 percent / 30 h / Heating View Scheme
参考文献
Sansebastiano; Mosti; Menozzi; Schenone; Muratore; Petta; Debbia; Pesce Schito; Schito
Farmaco, 1993 , vol. 48, # 3 p. 335 - 355
反应条件
1: ethyl acetate / 12 h / 110 °C / |Sealed tube
2: ammonium chloride / methanol / 48 h / 120 °C / |Sealed tube
View Scheme
参考文献
MERCK PATENT GMBH; BURGDORF, Lars; KUHN, Daniel; ROSS, Tatjana; DEUTSCH, Carl
Patent: WO2014/23385 A1, 2014 ;
反应条件
dihydrogen peroxide; sodium tungstate in water; acetic acid
T=30°C; 0.5 h;
参考文献
KUMIAI CHEMICAL INDUSTRY CO., LTD.; Ihara Chemical Industry Co., Ltd.
Patent: EP1439169 A1, 2004 ;
Location in patent: Page 95 ;
