1-甲氧基-9H-咔唑-3-甲醛合成路线 （共 24 条）
反应条件
methanol; copper(l) iodide in N,N-dimethyl-formamide
T=120°C; 5 h; Inert atmosphere;
参考文献
Bhosale, Shrikar M.; Momin, Aadil A.; Kusurkar, Radhika S.
Tetrahedron, 2012 , vol. 68, # 32 p. 6420 - 6426
反应条件
acetic acid; palladium diacetate
T=160°C; 12 h;
参考文献
Benavides, Adriana; Peralta, Javier; Delgado, Francisco; Tamariz, Joaquin
Synthesis, 2004 , # 15 p. 2499 - 2504
反应条件
sodium carbonate; lithium chloride; tetrakis(triphenylphosphine) palladium(0) in acetonitrile
48 h; Heating;
参考文献
Bernal, Pablo; Tamariz, Joaquin
Helvetica Chimica Acta, 2007 , vol. 90, # 8 p. 1449 - 1454
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene
4 h; Ambient temperature;
参考文献
Bringmann, Gerhard; Ledermann, Alfons; Holenz, Joerg; Kao, Muh-Tsuen; Busse, Ulrich; Wu, Howard G.; Francois, Guido
Planta Medica, 1998 , vol. 64, # 1 p. 54 - 57
反应条件
1: 96 percent / hydrogen / 10percent Pd/C / ethanol / 912 Torr
2: 2) MnO2 / 1) CH3CN, 46 h, RT, 2) toluene, RT 24 h and 2 d
View Scheme
参考文献
Knoelker, Hans-Joachim; Bauermeister, Michael
Tetrahedron, 1993 , vol. 49, # 48 p. 11221 - 11236
反应条件
1: BF3*Et2O / CH2Cl2 / 2.5 h / 160 °C
2: 69 percent / DDQ / benzene / 24 h / Heating
3: 81 percent / aq. NaOH / ethanol / 1 h / 20 °C
4: 95 percent / K2CO3 / acetone / 3 h / 60 °C
5: 73 percent / glacial acetic acid / Pd(OAc)2 / 12 h / 160 °C
View Scheme
参考文献
Benavides, Adriana; Peralta, Javier; Delgado, Francisco; Tamariz, Joaquin
Synthesis, 2004 , # 15 p. 2499 - 2504
反应条件
1: 95 percent / K2CO3 / acetone / 3 h / 60 °C
2: 73 percent / glacial acetic acid / Pd(OAc)2 / 12 h / 160 °C
View Scheme
参考文献
Benavides, Adriana; Peralta, Javier; Delgado, Francisco; Tamariz, Joaquin
Synthesis, 2004 , # 15 p. 2499 - 2504
反应条件
1: 81 percent / aq. NaOH / ethanol / 1 h / 20 °C
2: 95 percent / K2CO3 / acetone / 3 h / 60 °C
3: 73 percent / glacial acetic acid / Pd(OAc)2 / 12 h / 160 °C
View Scheme
参考文献
Benavides, Adriana; Peralta, Javier; Delgado, Francisco; Tamariz, Joaquin
Synthesis, 2004 , # 15 p. 2499 - 2504
反应条件
1: 69 percent / DDQ / benzene / 24 h / Heating
2: 81 percent / aq. NaOH / ethanol / 1 h / 20 °C
3: 95 percent / K2CO3 / acetone / 3 h / 60 °C
4: 73 percent / glacial acetic acid / Pd(OAc)2 / 12 h / 160 °C
View Scheme
参考文献
Benavides, Adriana; Peralta, Javier; Delgado, Francisco; Tamariz, Joaquin
Synthesis, 2004 , # 15 p. 2499 - 2504
反应条件
1: 65 percent / DDQ / benzene / 24 h / Heating
2: KOH / ethanol; H2O / 18 h / 20 °C
3: 0.24 g / K2CO3 / acetone / 12 h / Heating
4: 85 percent / Na2CO3; LiCl / [Pd(PPh3)4] / acetonitrile / 48 h / Heating
View Scheme
参考文献
Bernal, Pablo; Tamariz, Joaquin
Helvetica Chimica Acta, 2007 , vol. 90, # 8 p. 1449 - 1454
