N-乙酰基-L-半胱氨酸合成路线 （共 25 条）
参考文献
Martin,T.A. et al.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 3 p. 625 - 627
反应条件
1: 1 N aq. sodium hydroxide / 0.03 h / 65 °C
2: sodium / liquid ammonia / 0.75 h
View Scheme
参考文献
Glass, Richard S.; Farooqui, Firdous; Sabahi, Mahmood; Ehler, Kenneth W.
Journal of Organic Chemistry, 1989 , vol. 54, # 5 p. 1092 - 1097
反应条件
hydrogenchloride in water
T=37°C; Rate constant;
参考文献
Braendstroem, Arne; Lindberg, Per; Bergman, Nils-Ake; Tekenbergs-Hjelte, Lija; Ohlson, Kristina
Acta Chemica Scandinavica, 1989 , vol. 43, # 6 p. 577 - 586
反应条件
quantitative and qualitative effects of various stabilizers; Product distribution;
参考文献
Raether; Pause
Pharmazie, 1989 , vol. 44, # 10 p. 702 - 704
反应条件
in water
T=25°C; spectroscopic method, variation of the pH: the rate constant for the thiol-disulfide exchange (kSH) and for the thiolate ion-disulfide exchange (Ks-) as well as the activation energy were determined; Rate constant;
参考文献
Ozawa, Toshihiko; Hanaki, Akira
Chemical & Pharmaceutical Bulletin, 1981 , vol. 29, # 4 p. 1101 - 1105
