2-氨基-4-甲基戊腈盐酸盐合成路线 （共 7 条）
参考文献
Paventi, Martino; Edward, John T.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289
反应条件
ammonia in methanol
T=40°C; 2 h; Yield given;
参考文献
Mai; Patil
Tetrahedron Letters, 1984 , vol. 25, # 41 p. 4583 - 4586
反应条件
hydrogenchloride; ammonium chloride
1.) ammonium hydroxide, THF, 1.5 h (in a stoppered flask), 2.) ethyl ether; Yield given. Multistep reaction;
参考文献
Paventi, Martino; Edward, John T.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289
反应条件
in dichloromethane; water
pH=9;
参考文献
DSM IP Assets B.V.
Patent: EP1352894 A1, 2003 ;
Location in patent: Page/Page column 4-5 ;
反应条件
triethylamine in dichloromethane
5 h; Ambient temperature;
参考文献
Lipshutz, Bruce H.; Hungate, Randall W.; NcCarthy, Keith E.
Journal of the American Chemical Society, 1983 , vol. 105, # 26 p. 7703 - 7713
反应条件
1: 97 percent / Et3N / CH2Cl2 / 5 h / Ambient temperature
2: 70 percent / BF3*Et2O / CHCl3 / 2 h / 0 °C
View Scheme
参考文献
Lipshutz, Bruce H.; Hungate, Randall W.; NcCarthy, Keith E.
Journal of the American Chemical Society, 1983 , vol. 105, # 26 p. 7703 - 7713
反应条件
1: 97 percent / Et3N / CH2Cl2 / 5 h / Ambient temperature
2: 46 percent / BF3*Et2O / CHCl3 / 18 h / Ambient temperature
View Scheme
参考文献
Lipshutz, Bruce H.; Hungate, Randall W.; NcCarthy, Keith E.
Journal of the American Chemical Society, 1983 , vol. 105, # 26 p. 7703 - 7713
