2-氨基-4-甲基噻唑-5-甲酸乙酯合成路线 （共 37 条）
参考文献
Atkins, Elaine F.; Dabbs, Steven; Guy, Robert G.; Mahomed, Akbar A.; Mountford, Philip
Tetrahedron, 1994 , vol. 50, # 24 p. 7253 - 7264
反应条件
N-bromosuccinmide; xanthan sulfuric acid T=20°C; 0.25 h;
参考文献
Kuarm, Bowroju S.; Madhav, Janganati V.; Rajitha, Bhargavi
Letters in Organic Chemistry, 2011 , vol. 8, # 8 p. 549 - 553
反应条件
bromine; thiourea in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; diethyl ether; ethanol; water
参考文献
Abbott Laboratories
Patent: US6277871 B1, 2001 ;
反应条件
potassium carbonate in tetrahydrofuran Cyclization; 120 h; Heating;
参考文献
Park, Young Seok; Kim, Kyongtae
Tetrahedron Letters, 1999 , vol. 40, # 35 p. 6439 - 6442
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.2 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.2 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Zav'yalov; Dorofeeva; Rumyantseva; Kulikova; Ezhova; Kravchenko; Zavozin
Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 2 p. 96 - 98
反应条件
sodium hydrogencarbonate
参考文献
Journal of the American Chemical Society, , vol. 69, p. 1813
反应条件
1: 61 percent / dimethylsulfoxide / 3 h / 120 °C 2: 98 percent / K2CO3 / tetrahydrofuran / 120 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 40, # 35 p. 6439 - 6442
参考文献
Chemische Berichte, , vol. 29, p. 1045
Justus Liebigs Annalen der Chemie, , vol. 278, p. 79
