3-(1-苯并呋喃-3-基)丙氨酸合成路线 （共 9 条）
反应条件
hydrogenchloride
4 h; Heating;
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
Title/Abstract View citing articles Show Details
Podea, Paula Veronica; Tosa, Monica Ioana; Paizs, Csaba; Irimie, Florin Dan
Tetrahedron Asymmetry, 2008 , vol. 19, # 4 p. 500 - 511
反应条件
1: NaOH / methanol / 20 h / 20 °C
2: p-xylene / 2 h / Heating
3: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: SeO2 / dioxane / 48 h / Heating
2.1: NaBH4 / methanol / 20 °C
3.1: SOCl2; benzotriazole / CH2Cl2
4.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
4.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
5.1: NaOH / methanol / 20 h / 20 °C
6.1: p-xylene / 2 h / Heating
7.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: SOCl2; benzotriazole / CH2Cl2
2.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
2.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
3.1: NaOH / methanol / 20 h / 20 °C
4.1: p-xylene / 2 h / Heating
5.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: NaBH4 / methanol / 20 °C
2.1: SOCl2; benzotriazole / CH2Cl2
3.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
3.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
4.1: NaOH / methanol / 20 h / 20 °C
5.1: p-xylene / 2 h / Heating
6.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
1.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
2.1: NaOH / methanol / 20 h / 20 °C
3.1: p-xylene / 2 h / Heating
4.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: 97 percent / Na2CO3; H2O / 1 h / Heating
2.1: NaOAc; Ac2O / 3 h / 160 °C
3.1: SeO2 / dioxane / 48 h / Heating
4.1: NaBH4 / methanol / 20 °C
5.1: SOCl2; benzotriazole / CH2Cl2
6.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
6.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
7.1: NaOH / methanol / 20 h / 20 °C
8.1: p-xylene / 2 h / Heating
9.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: NaOAc; Ac2O / 3 h / 160 °C
2.1: SeO2 / dioxane / 48 h / Heating
3.1: NaBH4 / methanol / 20 °C
4.1: SOCl2; benzotriazole / CH2Cl2
5.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
5.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
6.1: NaOH / methanol / 20 h / 20 °C
7.1: p-xylene / 2 h / Heating
8.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
1.1: 58 percent / K2CO3 / acetone / 58 h / Heating
2.1: 97 percent / Na2CO3; H2O / 1 h / Heating
3.1: NaOAc; Ac2O / 3 h / 160 °C
4.1: SeO2 / dioxane / 48 h / Heating
5.1: NaBH4 / methanol / 20 °C
6.1: SOCl2; benzotriazole / CH2Cl2
7.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C
7.2: 81 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C
8.1: NaOH / methanol / 20 h / 20 °C
9.1: p-xylene / 2 h / Heating
10.1: 92 percent / aq. HCl / 4 h / Heating
View Scheme
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
