2-(2-N,N-二丙基氨基乙基)-6-硝基苯乙酸合成路线 （共 7 条）
反应条件
ammonium formate; palladium 10 on activated carbon in isopropyl alcohol T=20 - 80°C; 2 h; Product distribution / selectivity;
参考文献
Matera, Carlo; Quadri, Marta; Pelucchi, Silvia; De Amici, Marco; Dallanoce, Clelia
Monatshefte fur Chemie, 2014 , vol. 145, # 7 p. 1139 - 1144
反应条件
1: SOCl2
2: Na2CO3 / toluene; H2O / 1.5 h / 10 - 20 °C
3: 83 percent / borane/THF / 1 h / Heating
4: 1.) EtOK, 3.) H2O
5: aq. NaOH, H2O2 / 1 h / Ambient temperature
View Scheme
参考文献
DeMarinis, Robert M.; Gallagher, Gregory; Hall, Ralph F.; Franz, Robert G.; Webster, Charles; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 939 - 947
反应条件
1: Na2CO3 / toluene; H2O / 1.5 h / 10 - 20 °C
2: 83 percent / borane/THF / 1 h / Heating
3: 1.) EtOK, 3.) H2O
4: aq. NaOH, H2O2 / 1 h / Ambient temperature
View Scheme
参考文献
DeMarinis, Robert M.; Gallagher, Gregory; Hall, Ralph F.; Franz, Robert G.; Webster, Charles; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 939 - 947
反应条件
dihydrogen peroxide in dihydrogen peroxide
T=80°C; 5 h;
参考文献
Krishnaiah; Murthy, M. Vishnu; Reddy, A. Raghupathi; Kumar, Ramesh; Mukkanti
Journal of the Chinese Chemical Society, 2010 , vol. 57, # 3 A p. 348 - 355
反应条件
sodium hydroxide; dihydrogen peroxide
1 h; Ambient temperature;
参考文献
DeMarinis, Robert M.; Gallagher, Gregory; Hall, Ralph F.; Franz, Robert G.; Webster, Charles; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 939 - 947
反应条件
1: 1.) EtOK, 3.) H2O
2: aq. NaOH, H2O2 / 1 h / Ambient temperature
View Scheme
参考文献
DeMarinis, Robert M.; Gallagher, Gregory; Hall, Ralph F.; Franz, Robert G.; Webster, Charles; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 939 - 947
反应条件
1: 83 percent / borane/THF / 1 h / Heating
2: 1.) EtOK, 3.) H2O
3: aq. NaOH, H2O2 / 1 h / Ambient temperature
View Scheme
参考文献
DeMarinis, Robert M.; Gallagher, Gregory; Hall, Ralph F.; Franz, Robert G.; Webster, Charles; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 939 - 947
