3-甲基-2-苯基-4H-1-苯并吡喃-4-酮合成路线 （共 23 条）
反应条件
1: 80 percent / NBS / CCl4 / 4 h / Heating; Irradiation 2: acetic acid / 12 h / Heating 3: H3O(1+) View Scheme
参考文献
Wurm, Gotthard; Nordmann, Matthias
Archiv der Pharmazie (Weinheim, Germany), 1988 , vol. 321, p. 555 - 558
反应条件
1: 1-(2-hydroxyphenyl)-1-propanone With lithium hexamethyldisilazane in toluene
T=0°C; 0.5 h; Sealed tubeInert atmosphere;
2: benzoyl chloride in toluene
T=20°C; 27 h; Cooling with iceInert atmosphere;
3: With hydrogenchloride in toluene
T=20°C; 72 h; Inert atmosphere; Time;
参考文献
Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.
Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-D0823-L, p. 2683 - 2686
反应条件
1: C34H26O2P(1+)*Br(1-) With sodium hydride in tetrahydrofuran
T=20°C; 0.5 h;
2: benzoyl chloride in tetrahydrofuran
T=20°C; Wittig Olefination; 6 h; Time;
参考文献
Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.
Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-D0823-L, p. 2683 - 2686
反应条件
palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=120°C; P=3750.38 Torr; 16 h; Autoclave;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemistry - A European Journal, 2012 , vol. 18, # 40 p. 12595 - 12598
反应条件
tetrabutylammomium bromide in N,N-dimethyl-formamide
T=100°C; 15 h;
参考文献
Patonay, Tamas; Patonay-Peli, Erzsebet; Litkei, Gyoegy; Szilagyi, Laszlo; Batta, Gyula; Dinya, Zoltan
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 343 - 347
反应条件
iodine in dimethyl sulfoxide
Reflux;
参考文献
Jayashree, B. S.; Alam, Afroze; Vijay Kumar, D.; Nayak, Yogendra
Medicinal Chemistry Research, 2012 , vol. 21, # 8 p. 1991 - 1996,6
Title/Abstract Show Details
Jayashree; Alam, Afroze; Nayak, Yogendra; Vijay Kumar
Medicinal Chemistry Research, 2012 , vol. 21, # 8 p. 1991 - 1996
反应条件
C5H5*HCl
T=200°C; 5 h;
参考文献
Makrandi, J K; Kumari, Vandna
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1991 , vol. 30, # 12 p. 1142 - 1144
反应条件
18-crown-6 ether in acetonitrile
114 h; Heating;
参考文献
Patonay, Tamas; Patonay-Peli, Erzsebet; Litkei, Gyoegy; Szilagyi, Laszlo; Batta, Gyula; Dinya, Zoltan
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 343 - 347
反应条件
hydrogenchloride in acetic acid
T=100 - 110°C; Yield given;
参考文献
Hirao, Ichiro; Yamaguchi, Masahiko; Hamada, Michiyuki
Synthesis, 1984 , # 12 p. 1076 - 1078
反应条件
1: 36 percent / pyridine / 216 h / Ambient temperature
2: 84 percent / 18-crown-6 / acetonitrile / 114 h / Heating
View Scheme
参考文献
Patonay, Tamas; Patonay-Peli, Erzsebet; Litkei, Gyoegy; Szilagyi, Laszlo; Batta, Gyula; Dinya, Zoltan
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 343 - 347
