2-氨基-5-氯二苯甲酮合成路线 （共 174 条）
反应条件
copper(l) iodide; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; oxygen; (R)-(+)-1,1'-binaphthyl-2,2'-diamine in toluene T=60°C; 48 h;
参考文献
Mannam, Sreedevi; Sekar, Govindasamy
Tetrahedron Asymmetry, 2009 , vol. 20, # 4 p. 497 - 502
反应条件
trimethylsilyl iodide; water in acetonitrile T=20°C; 0.2 h;
参考文献
Boruah, Monalisa; Konwar, Dilip
Journal of Chemical Research - Part S, 2002 , # 12 p. 601 - 603
反应条件
1: 2-aminophenyl-phenylmethanone With tert-butylhypochlorite in dichloromethane T=-70°C; 0.166667 h; 2: 2-(methylthio)acetamide in tetrahydrofuran; dichloromethane T=-70 - 0°C; 3: With triethylamine in tetrahydrofuran; dichloromethane T=0 - 20°C;
参考文献
US2009/312575 A1, ;
Page/Page column 5 ;
反应条件
gallium(III) chloride; boron trichloride in chlorobenzene T=100°C; 20 h;
参考文献
Houpis, Ioannis N.; Molina, Audrey; Douglas, Alan W.; Xavier, Lyndon; Lynch, Joseph; et al.
Tetrahedron Letters, 1994 , vol. 35, # 37 p. 6811 - 6814
反应条件
sulfuric acid in ethanol T=40°C; 1.16667 h;
参考文献
Pflegel; Kuhmstedt; Mann; Richter
Pharmazie, 1985 , vol. 40, # 10 p. 710 - 713
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; oxygen; copper(II) bis(trifluoromethanesulfonate); (R)-(+)-1,1'-binaphthyl-2,2'-diamine in toluene T=80°C; 11 h; optical yield given as percent ee;
参考文献
Mannam, Sreedevi; Sekar, Govindasamy
Tetrahedron Asymmetry, 2009 , vol. 20, # 4 p. 497 - 502
反应条件
zinc(II) chloride T=100 - 180°C; dann auf 200-220grad und Spalten des Produkts durch Kochen mit Alkohol und konz. Salzsaeure oder durch Erhitzen mit starker Schwefelsaeure;
参考文献
Journal of the Chemical Society, , vol. 101, p. 516
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; oxygen; copper(II) bis(trifluoromethanesulfonate); (R)-(+)-1,1'-binaphthyl-2,2'-diamine in toluene T=60°C; 24 h; optical yield given as percent ee;
参考文献
Mannam, Sreedevi; Sekar, Govindasamy
Tetrahedron Asymmetry, 2009 , vol. 20, # 4 p. 497 - 502
反应条件
1: in tetrahydrofuran T=0 - 80°C; 2: With hydrogenchloride in tetrahydrofuran; water T=0 - 20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 22 p. 7289 - 7300
反应条件
hydrazine hydrate in ethanol; chloroform 15 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 46, # 22 p. 4489 - 4493
